Fluorine in Heterocyclic Chemistry
(Sprache: Englisch)
This book details the chemistry of fluorinated heterocycles, which are important in the pharmaceutical industry, materials science and agriculture. It clearly presents and classifies all information, making it an effective source for a broad range of chemists.
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Produktinformationen zu „Fluorine in Heterocyclic Chemistry “
This book details the chemistry of fluorinated heterocycles, which are important in the pharmaceutical industry, materials science and agriculture. It clearly presents and classifies all information, making it an effective source for a broad range of chemists.
Klappentext zu „Fluorine in Heterocyclic Chemistry “
The present work combines comprehensive information on chemistry of fluorinated heterocycles of interest to synthetic organic chemists in general, and particularly for those colleagues working in the fields of chemistry of heterocyclic compounds, medicinal chemistry, materials chemistry, fluorine chemistry. All information is presented and classified clearly to be effective source for broad auditory of chemists. It will be interesting for scientists working in the field of inorganic and coordination chemistry. Fluorinated heterocycles are becoming increasingly important in the pharmaceutical industry, materials science and agriculture. The presence of fluorine can result in substantial functional changes in the biological as well as physicochemical properties of organic compounds. Incorporation of fluorine into drug molecules can highly affect their physicochemical properties, such as bond strength, lipophilicity, bioavailability, conformation, electrostatic potential, dipole moment, pKa etc; pharmacokinetic properties, such as tissue distribution, rate of metabolism; and pharmacological consequences, such as pharmacodynamics and toxicology.
Inhaltsverzeichnis zu „Fluorine in Heterocyclic Chemistry “
Pyrrole.- Furan, benzofuran.-Thiophene, benzothiophene.- Indole.- 1,2-Azole (pyrazole, isoxasole, isothiazole) and benzoanalogues.- 1,3-Azole (imidazole, thiazole, oxazole) and benzoanalogues.- Pyridine.- Quinoline and Quinolones.- Isoquinoline.- Pyrimidine, pyrazine, pyridazine.- Triazines.- Purines.- Triazole (benzotriazole) and tetrazole.- Heterocycles with nitrogen junction.- Fluorinated pyrans (thiopyrans) and benzoanalogues.- Porphyrins and phthalocyanins.- Fluorinated Porphyrazines.- Fluorine and heterocycles two privilege units for medicinal chemistry.- Fluorine and new materials.- Fluorinated dihetarylethenes as a new photochromic materials.- 18F heterocycles in positron emission tomography.
Autoren-Porträt von Valentine Nenajdenko
Valentine G. Nenajdenko was born in 1967 in Ivanovo, Russia. He graduated from Moscow State University (Lomonosov) in 1991. He received his Ph.D. degree under the supervision of Professor E.S. Balenkova in 1994 researching the synthesis and application of unsaturated CF3 ketones. In 2000 he received Dr. of Chemistry degree involving the chemistry of sulfonium and iminium salts. In 2003 he became full Professor of Organic Chemistry at the Department of Chemistry of Moscow State University. His scientific interests include organic synthesis, asymmetric catalysis, the chemistry of sulfur and fluorine containing compounds, heterocyclic chemistry, multicomponent reactions. He have been a supervisor of 12 postgraduate studies. Prof. Nenajdenko is head of the Scientific Committee and Jury of International Mendeleev Chemistry Olympiad. He was the winner of the Academiae Europeae Award in 1997, the Russian President Award in 1996, the Prize for the best scientific work at the Department of Chemistry of Moscow State University in 2001 and 2007, the Shuvalov Award in 2001, the Russian President Award in 2004, Russian Science Support Foundation in 2005, Moscow State University Awards in 2006, 2007 and 2008.
Bibliographische Angaben
- Autor: Valentine Nenajdenko
- 2014, 700 Seiten, 200 Abbildungen, Maße: 23,5 cm, Gebunden, Englisch
- Verlag: Springer
- ISBN-10: 3709106893
- ISBN-13: 9783709106891
Sprache:
Englisch
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