Formulation and Evaluation of Fast Dissolving Tablet of Clopidogrel
Fast Dissolving Tablets
(Sprache: Englisch)
The present investigation involves formulation and evaluation of fast dissolving tablet of clopidogrel, which is used to prevent coronary disorder. Platelet aggregation is part of the sequence events leading to the formulation of a thrombus (clot)....
Leider schon ausverkauft
versandkostenfrei
Buch
54.90 €
Produktdetails
Produktinformationen zu „Formulation and Evaluation of Fast Dissolving Tablet of Clopidogrel “
Klappentext zu „Formulation and Evaluation of Fast Dissolving Tablet of Clopidogrel “
The present investigation involves formulation and evaluation of fast dissolving tablet of clopidogrel, which is used to prevent coronary disorder. Platelet aggregation is part of the sequence events leading to the formulation of a thrombus (clot). Antiplatelet therapy with one or more drugs decreases the ability of blood clot to form by interfering with the platelet activation process in primary homeostasis. Tablets were formulated by three different methods Viz., Direct compression method, Solid dispersion method and Sublimation method. Different excipients such as, crospovidone as super disintegrants, croscarmellose as superdisintegrant, magnesium stearate as lubricant, talc as glidant etc. were used. Based on in-vitro release studies tablets prepared by sublimation method clopidogrel was selected as optimizes formulation. In-vitro release studies indicated more than 95% release of drug in 30 mins. The accurate stability studies indicated no change in in-vitro release and other property of the tablet. Thus sublimation method can be a promising strategy in enhancing the solubility and dissolution studies of clopidogrel bisulphate.
Autoren-Porträt von Vinay Pandit, M. S. Ashawat, Surbhi Dutta
Pandit, VinayDr. Vinay Pandit is working as Professor and Head, Department of Pharmaceutics, Laureate Institute of Pharmacy, Kathog, Jawlamukhi, Himachal Pradesh. He has published a number of research articles in various reputed journals nationally and internationally. His area of research is fast dissolving technology and chronotherapeutics.
Bibliographische Angaben
- Autoren: Vinay Pandit , M. S. Ashawat , Surbhi Dutta
- 2020, 108 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 6200535078
- ISBN-13: 9786200535078
Sprache:
Englisch
Kommentar zu "Formulation and Evaluation of Fast Dissolving Tablet of Clopidogrel"
0 Gebrauchte Artikel zu „Formulation and Evaluation of Fast Dissolving Tablet of Clopidogrel“
Zustand | Preis | Porto | Zahlung | Verkäufer | Rating |
---|
Schreiben Sie einen Kommentar zu "Formulation and Evaluation of Fast Dissolving Tablet of Clopidogrel".
Kommentar verfassen