Gene Regulation, Epigenetics and Hormone Signaling

VOLUME 1Eukaryotic Gene Expression by RNA Polymerase IIEpigenetic Code: Histone Modification, Gene Regulation, and Chromatin DynamicsHistone Lysine Methylation, Demethylation, and Hormonal Gene RegulationThe Role of HATs and HDACs in Cell Physiology and DiseaseThe Short and Medium Stories of Noncoding RNAs: microRNA and siRNALong Noncoding RNA (lncRNA): Functions in Health and DiseaseHistone Variants: Structure, Function, and Implication in DiseasesGenomic Imprinting in Mammals: Origin and Complexity of an Epigenetically Regulated PhenomenonCentromere and Kinetochore: Essential Components for Chromosome SegregationNuclear Receptors and NR-coregulators: Mechanism of Action and Cell SignalingVOLUME 2Estrogen and Progesterone Receptor Signaling and ActionGonadal Steroid Hormones and Brain ProtectionGlucocorticoid Receptor-Mediated Signaling and Stress MetabolismTargeting Androgen Signaling in Prostate CancerRole of Peroxisome Proliferator-Activated Receptors in Inflammation and AngiogenesisRAR/RXR-Mediated SignalingOn the Trail of Thyroid Hormone Receptor EpigeneticsInsulin Signaling, Epigenetics, and Human DiseasesEndocrine Disruptors and EpigeneticsEndocrine Disruptors: Mechanism of Action and Impacts on Health and Environment

Subhrangsu S. Mandal is currently Associate Professor at the Department of Chemistry and Biochemistry, at The University of Texas at Arlington, Texas. He received his PhD degree from the Indian Institute of Science, Bangalore, where he worked on chemical nucleases and cationic liposome-mediated gene delivery in the laboratory of Professor S. Bhattacharya. He joined the laboratory of Professor Linda J. Reha-Krantz as an Alberta Heritage Foundation for Medical Research (AHFMR) postdoctoral fellow in the University of Alberta, Canada. He later moved to the laboratory of Professor Danny Reinberg to research on eukaryotic transcription and gene regulation in human at the University of Medicine and Dentistry of New Jersey (UMDNJ)/Howard Hughes Medical Institute (HHMI). Prof. Mandal began his independent career at University of Texas at Arlington in 2005. Specifically he is investigating the function of Mixed Lineage Leukemia (MLL) family of histone methyl-transferases in gene activation, estrogen signalling, and tumorigenesis. In parallel, the Mandal laboratory is also developing novel gene targeted cancer therapy using mouse models.