Gene Regulation

Tissue-specific expression of proteins and messenger RNAs. The DNA of different cell types is similar in both amount and type. Regulation at transcription. Post-transcriptional regulation. Transcriptional control - chromatin structure. Transcriptional control - DNA sequence elements. Transcriptional control - transcription factors. Gene regulation and cancer. Conclusions and future prospects. Index.

Reviews from the first edition:; It is well written, lucid and makes easy reading. The illustrations are well thought out, plentiful, and easy to follow. There is an excellent reference list at the end of each chapter - Society for General Microbiology Quarterly; The text is lucid and free of jargon and generally a pleasure to read - The Lancet; Latchman has done a grand job of synthesis, and these chapters could form a useful background to more seasoned workers than undergraduates...Readers will be rewarded by an up-to-date, but very succinct, account of progress in an exciting and important area of modern biology - Times Higher Education Supplement; This is a timely and attractive short textbook that will be of considerable value to senior undergraduates, postgraduates, those entering the field for the first time, and their teachers. I shall be enthusiastically recommending it to my students; perhaps then they will understand my lectures and be able to answer the examination questions! - Applied Biodiversity and Biotechnology; This is an excellent student book. - Cellular and Molecular Biology; Rather than compiling a dry series of facts, an excellent pedagogue has threaded through the various chapters a logical scheme that allows smooth transitions from one regulatory mechanism to another and makes the reading actually quite enjoyable. Practical examples are judiciously chosen and introduced with extreme clarity...this book does a wonderful job of mentioning everyone's favourite hypotheses while placing them in a larger context and keeping alternative possibilities and interpretations wide open. Latchman's review should be highly recommended to motivated undergraduate and graduate students who want to immerse themselves in the facinating world of gene regulation - Trends in Genetics; The fast pace of research in this field makes the task of distilling it to under 300 pages a daunting one, but Latchman has succeeded admirably. The straighforward style of the text