High Throughput Screening

Design and Implementation of High Throughput Screening Assays.- Characterization of InhibitorBinding Through Multiple Inhibitor Analysis: A Novel Local Fitting Method.- High Throughput Screening UsingMass Spectrometry within Drug Discovery.- Structure-Based Virtual Screeningof Commercially Available Compound Libraries.- AlphaScreen-Based Assays:Ultra-High Throughput Screening for Small Molecule Inhibitors of ChallengingEnzymes and Protein-Protein Interactions.- Instrument Quality Control.- Application of FluorescencePolarization in HTS Assays.- Time Resolved Fluorescence Assays.- Protein Kinase SelectivityProfiling Using Microfluid Mobility Shift Assays.- Screening for Inhibitors ofKinase Autophosphorylation.- A Fluorescence-Based HighThroughput Screening Assay to Identify Growth Inhibitors of the PathogenicFungus Aspergillus fumigatus.- Mycobacterium tuberculosisHigh Throughput Screening.- Identification ofState-Dependent Blockers for Voltage Gated Calcium Channels Using a FLIPR BasedAssay.- A Luciferase Reporter GeneSystem for High Throughput Screening of Gamma-Globin GeneActivators.- A High Throughput Flow CytometryAssay for Identification of Inhibitors of 3', 5'-Cyclic Adenosine MonophosphateEfflux.- High Throughput Cell ToxicityAssays.- BRETn: NanoLuc-BasedBioluminescence Resonance Energy Transfer Platform to Monitor Protein-ProteinInteractions in Live Cells.- Application of Imaging-BasedAssays in Microplate Formats for High Content Screening.