Interferon LAMBDA-3: Immune Modulator
Role of pcDNA-Interferon LAMBDA-3 (pcDNA-IFNL3) as Immune Modulator
(Sprache: Englisch)
Interferon Lambdas (IFNLs) is a type III IFN which induces expression of Interferon Stimulated Genes (ISGs). These ISGs in turn participate in antiviral and other interferon related activities. IFNLs are found to have immune modulation activities in...
Leider schon ausverkauft
versandkostenfrei
Buch
39.90 €
Produktdetails
Produktinformationen zu „Interferon LAMBDA-3: Immune Modulator “
Klappentext zu „Interferon LAMBDA-3: Immune Modulator “
Interferon Lambdas (IFNLs) is a type III IFN which induces expression of Interferon Stimulated Genes (ISGs). These ISGs in turn participate in antiviral and other interferon related activities. IFNLs are found to have immune modulation activities in addition to antiviral activities. Immune modulation activities are advantageous for the host system for better protection against invading pathogens. In the present study, the vector construct of bovine Interferon lambda-3 (IFN-L3) was analyzed for its immune modulation activities. The IFNL3 gene of 585bp cloned in pcDNA3.1+ vector (pcDNA-IFNL3) was analyzed for its expression in baby hamster kidney (BHK) cell line by fluorescence microscopy. Bovine IFNL3 gene cloned in pcDNA3.1+ vector with downstream Green fluorescent protein (GFP) tag found to show the green fluorescence. This construct was further tested for its immune modulation activities in mice. At 7th day the Spleenocytes were collected from the mice and analyzed for activation of B and T lymphocytes by Fluorescent Activated Cell Sorting (FACS) using specific CD markers. The results showed that IFN 3 could activate both B and T lymphocyte population in treated mice.
Autoren-Porträt von Reddy G.R, Barathiraja S
S, BarathirajaI Dr. Barathiraja S, M.V.Sc., Ph.D pursued M.V.Sc from RIVER, Puducherry, India and Ph.D (Animal Biochemistry) from ICAR-IVRI, Hebbal, Bangalore, Karnataka under the mentor-ship of Dr.G.R.Reddy. At present I am working as Assistant Professor (C) in the Dept. of Veterinary Biochemistry, under the supervision of Dr.J.Thanislass, & Prof.S.Ramkumar.
Bibliographische Angaben
- Autoren: Reddy G.R , Barathiraja S
- 2019, 56 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 6200311811
- ISBN-13: 9786200311818
Sprache:
Englisch
Kommentar zu "Interferon LAMBDA-3: Immune Modulator"
0 Gebrauchte Artikel zu „Interferon LAMBDA-3: Immune Modulator“
Zustand | Preis | Porto | Zahlung | Verkäufer | Rating |
---|
Schreiben Sie einen Kommentar zu "Interferon LAMBDA-3: Immune Modulator".
Kommentar verfassen