Interrelationship Among Aging, Cancer and Differentiation

Interrelationships among Aging, Cancer and Differentiation.- Deceleration of Cancer Mortality Rates with Age and Time.- Clinical Aspects of Cancer in the Elderly.- Overview of the Pathobiology of Aging.- Regulators of Growth, Differentiation and the Reversal of Malignancy.- Transforming Genes of Human Malignancies.- Cancer Cells as Probes of Embryonic Development.- Alterations in Epidermal Differentiation in Skin Carcinogenesis.- Virus Transformation as a Function of Age, Differentiation and Hereditary Factors.- Negative Control of Viral and Cellular Enhancer Activity by the Products of the Immortalizing E1A Gene of Human Adenovirus-2.- Expression of two Murine Gene Families in Transformed Cells and Embryogenesis.- Methotrexate Resistance, Gene Amplification, and Somatic Cell Heterogeneity.- Macromolecular Correlates of Cellular Senescence and Cancer.- Dominance of in Vitro Senescence in Somatic Cell Hybridization and Biochemical Experiments.- Studies on Gene Structure and Function in Aging: Collagen Types I and II and the Albumin Genes.- Retrovirus-like Gene Families in Normal Cells : Potential for Affecting Cellular Gene Expression.- The Conformational Effects of UV Induced Damage on DNA.- DNA Supercoiling and Gene Expression.- Intermediates in Transcription Initiation and Propagation.- New Carbohydrate Binding Proteins (Lectins) in Human Cancer Cells and their Possible Role in Cell Differentiation and Metastasation.- Control of Gene Expression by Oligonucleoside Methylphosphonates.- Genetic Mechanisms in Tumor Progression, Heterogeneity, and Metastasis.- Genes, Fragile Sites, Chromosomal Translocations, and Cancer in Aging.- Comparison of Human and Rodent Cell Transformation by Known Chemical Carcinogens.- Critical Molecular Events and Gene Regulation in Carcinogenesis, Differentiation and Aging.- Monoclonal Antibodies Directed against Alkyl-Deoxynucleosides and Cell Type- and Differentiation Stage-Specific Cell Surface Determinants in the Study of