Intracellular Niches of Microbes

Introduction (Schaible and Haas)

General chapters (each by an invited contributor)
The evolution of intracellular microbes: from amoeba survivors to intracellular pathogens of mammals (Schaible and Haas)
What's in it for a microbe and how does it adapt? (Schaible and Haas)
Overview: Everybody has a home of their own (Haas)
Gene transfer in evolution of intracellular parasitism
Engulfment Uptake ("It started with a kiss" and run???)
Cellular model systems to study phagosome biogenesis
Toolbox: How to study phagosome maturation
Phagosome-cytoskeleton interactions
In vitro assays with phagosomes
Intracellular expression profiling
Proteomics and the biology of phagosome development
Immunity to intracellular pathogens (Schaible)
Consequences of compartmentation for therapeutic intervention (Schaible and Haas)

Chapters on individual pathogens (each by an invited contributor)
Intraphagosomal bacteria
Afipia
Brucella
Burkholderia pseudomallei
Chlamydia
Coxiella
Ehrlichia, Anaplasma
Francisella
Legionella pneumophila
Mycobacterium marinum
Mycobacterium tuberculosis vs. M. avium, M. bovis BCG, M. leprae
Rhodococcus, Nocardia
Salmonella

Intracytoplasmic bacteria
Listeria
Rickettsia
Shigella

Intracellular symbionts
Amoeba symbionts
Wohlbachia
Bacterial symbionts in plants
Algal Symbionts

Parasites and fungi
Histoplasma
Leishmania
Plasmodium and Babesia
Theileria
Toxoplasma gondii

Ulrich Schaible is Professor of Immunology at London School of Hygiene & Tropical Medicine, UK. After graduating from Freiburg University, he obtained his PhD working with Marcus Simon at the Max-Planck-Institute of Immunobiology, Freiburg. After a postdoc with David Russell at Washington University, St. Louis, USA, he joined the department of Stefan Kaufmann at the Max-Planck-Institute of Infection Biology, Berlin. He combines immunology and cellular microbiology to study host-pathogen-interactions in tuberculosis. He has authored 86 articles and received the Royal Society Wolfsohn Research Merit Award, the GlaxoSmithKline-Foundation for Clinical-Research-Award and the Otto-Westphal-Award of the German Society of Immunology.

Albert Haas was appointed Professor of Cell Biology at Bonn University in 2001. After graduating from Würzburg University, he obtained his PhD in Microbiology working with Werner Goebel on Listeria pathogenesis. After postdoctoral research in Bill Wickner's lab at UCLA (Los Angeles, CA) and Dartmouth College (Hanover, NH) on yeast cell biology, he returned to Würzburg University to start his independent research which focuses on questions of phagosome biogenesis. He has authored 35 articles and received the Vector-Laboratories Young Investigator Award (American Society for Microbiology), the Butenandt-Habilitation-Award and the Karl-Lohmann-Award, both from the German Society for Biochemistry and Molecular Biology.