Managing the Older Adult Patient with HIV
(Sprache: Englisch)
This concise, clinically focused pocket guide offers a complete overview of HIV in the older patient and reviews the latest guidelines, treatment options, clinical trials, and management of HIV within this subgroup. The easily accessible text offers...
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This concise, clinically focused pocket guide offers a complete overview of HIV in the older patient and reviews the latest guidelines, treatment options, clinical trials, and management of HIV within this subgroup. The easily accessible text offers infectious disease specialists and other health care professionals with an excellent quick reference tool, with full color tables and figures enhancing the text further. HIV is a chronic disease that affects the immune system, leading to AIDS. As treatments have progressed and patients with HIV are living longer a new aspect has to be taken in to consideration when treating HIV and other conditions. Comorbidities are rife within older adults with HIV, as many of the treatments for HIV cause long-term side effects, such as heart conditions and cancer. Special consideration must be taken to ensure no toxic drug-drug interactions between treatments.
Inhaltsverzeichnis zu „Managing the Older Adult Patient with HIV “
1. IntroductionReferences
2. Pathophysiology of HIV/AIDS
Key points
2.1 Immunodeficiency, immune activation, and chronic inflammation
2.2 HIV and immunosenescence
2.3 Evolving clinical profile
References
3. HIV associated non-AIDS conditions in patients aging with HIV
Key points
3.1 HIV-associated non-AIDS conditions versus comorbidities
References
4. Comorbid conditions and older adults with HIV
Key points4.1 Multimorbidity
4.2 Accentuated versus accelerated aging
4.3 Aging versus aged
References
5. Frailty in HIV
Key points
5.1 Defining frailty
5.2 Measuring frailty
5.3 The utility of measuring frailty
5.4 Frailty in the context of HIV
References
6. Disability
Key points
6.1 Overview
6.2 Functional impairment and disability in patients with HIV
6.3 Tools to measure disability6.4 Conclusion
References
7. Geriatric syndromes
Key points
7.1 Definition
7.2 Falls
7.3. Delirium
7.4 Conclusion
References
8. HIV prevention and screening in older adults
Key points
8.1 Age-related risk factors
8.2. Barriers to prevention
8.3. Screening and counselling opportunities
References
9. Multidimensional geriatric assessment in older patients with HIVKey points
References
10. Antiretroviral treatment in older patients
Key points
10.1 When to start antiretroviral therapy
10.2 What to start
10.3 What to change
10.4 Future perspectives
References
11. HIV, aging, and polypharmacy
Key points
References
12. Nutrition and physical exercise in older patients with HIV
Key points
12.1 Overview
12.2 Assessment of risk of malnutrition12.3 Intervention
12.4 Sarcopenic obesity
12.5 Physical exercise
12.6 Conclusion
References
13. Smoking cessation in patients with HIV
Key points
13.1 Pharmacological strategies to treat nicotine dependenceReferences
14. Self-management
Key points
References
Autoren-Porträt von Giovanni Guaraldi, Chiara Mussi, Julian Falutz, Ana Rita Silva
Giovanni Guaraldi, MD, is Assistant Professor of Infectious disease at University of Modena and Reggio Emilia, Italy, where he also completed his medical training. Dr Guaraldi undertook his residency at Liverpool School of Tropical Medicine, UK, and Jackson Memorial Hospital, USA. Dr Guaraldi was awarded the Dean's Delegate Cooperation for development projects of Modena University. He has extensive experience in HIV in resource limited countries and has coordinated the European Africa, Caribbean, Pacific project CoBaSys (Community Based System in HIV Treatment) focused on antiretroviral access programs in sub-Saharan African countries.
In 2002 Dr Guaraldi started a liver and kidney transplant program for people with HIV at the multivisceral transplant centre at Policlinico of Modena, Italy. Since the centre opened he has personally cared for approximately 80 patients with HIV who have received solid organ transplantation. Dr Guaraldi has lead the Modena HIV Metabolic Clinic since 2000. This referral centre cares for more than 4000 patients and offers a multidisciplinary team consisting of infectious disease physicians, nutritionists, occupational therapists, psychologists, cardiologists, nephrologists, endocrinologists, and plastic surgeons for the diagnosis and treatment of non-infectious comorbidities.
Dr Guaraldi has been the principal investigator in several studies generated by the MHMC, mainly focused on frailty and HIV associated comorbidities. He has extensive experience in scientific publication, with more than 260 peer reviewed papers, he is co-editor of Journal of Antimicrobial Chemotherapy, serves as reviewer for the major HIV journals, and as a consultant for EMA. He supervises PhD student in the Experimental Medicine PhD course at Modena University.
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Dr Guaraldi is a panel member of the European AIDS Clinical Society guidelines on prevention and management of HIV associated comorbidities and has published widely on clinical aspects of HIV treatment and care.
Julian Falutz MD, FRCP(C), is Assistant Professor of Medicine at McGill University and Associate Physician at the Montreal General Hospital Site of the McGill University Hospital Centre (MUHC), Canada. He is the Director of the Comprehensive HIV and Aging Initiative in the Chronic Viral Illness Service and a Senior Physician in the Division of Geriatrics at the MUHC.
Dr Falutz attended McGill University School of Medicine, where he completed his residency in General Internal Medicine and received subspecialty training in both Internal Medicine and Geriatrics. He has been actively involved in the clinical care of both HIV and geriatric patients at the MUHC for over 25 years. He is active as a clinical teacher at the undergraduate and graduate levels and was the Director of the HIV elective program at the MUHC for 20 years.
His research in HIV has focused on the interaction of immunodeficiency, nutrition, and metabolic complications. He has initiated and participated in numerous studies on the management of HIV-related complications. He was the Co-Principal Investigator for the pivotal multinational studies investigating a novel Growth Hormone Releasing Factor for the treatment of abdominal obesity in patients with HIV. The investigated drug has since been approved for use in both the US and Canada. He is the Canadian Coordinator for the REPRIEVE Study, a multinational study of statins to prevent cardiovascular disease in low-risk treated HIV patients. He has initiated a Program for the evaluation of patients aging with HIV and plays an active role in emerging studies evaluating frailty and comorbidities in patients aging with HIV.
Chiara Mussi, MD, PhD, is a Doctor in Medicine within the Modena HIV Me
Dr Guaraldi is a panel member of the European AIDS Clinical Society guidelines on prevention and management of HIV associated comorbidities and has published widely on clinical aspects of HIV treatment and care.
Julian Falutz MD, FRCP(C), is Assistant Professor of Medicine at McGill University and Associate Physician at the Montreal General Hospital Site of the McGill University Hospital Centre (MUHC), Canada. He is the Director of the Comprehensive HIV and Aging Initiative in the Chronic Viral Illness Service and a Senior Physician in the Division of Geriatrics at the MUHC.
Dr Falutz attended McGill University School of Medicine, where he completed his residency in General Internal Medicine and received subspecialty training in both Internal Medicine and Geriatrics. He has been actively involved in the clinical care of both HIV and geriatric patients at the MUHC for over 25 years. He is active as a clinical teacher at the undergraduate and graduate levels and was the Director of the HIV elective program at the MUHC for 20 years.
His research in HIV has focused on the interaction of immunodeficiency, nutrition, and metabolic complications. He has initiated and participated in numerous studies on the management of HIV-related complications. He was the Co-Principal Investigator for the pivotal multinational studies investigating a novel Growth Hormone Releasing Factor for the treatment of abdominal obesity in patients with HIV. The investigated drug has since been approved for use in both the US and Canada. He is the Canadian Coordinator for the REPRIEVE Study, a multinational study of statins to prevent cardiovascular disease in low-risk treated HIV patients. He has initiated a Program for the evaluation of patients aging with HIV and plays an active role in emerging studies evaluating frailty and comorbidities in patients aging with HIV.
Chiara Mussi, MD, PhD, is a Doctor in Medicine within the Modena HIV Me
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Bibliographische Angaben
- Autoren: Giovanni Guaraldi , Chiara Mussi , Julian Falutz , Ana Rita Silva
- 2016, 1st ed. 2016, XXII, 227 Seiten, 16 farbige Abbildungen, Maße: 12,8 x 20,3 cm, Kartoniert (TB), Englisch
- Herausgegeben: Giovanni Guaraldi, Julian Falutz, Chiara Mussi, Ana Rita Silva
- Verlag: Springer, Berlin
- ISBN-10: 3319201301
- ISBN-13: 9783319201306
- Erscheinungsdatum: 17.05.2016
Sprache:
Englisch
Pressezitat
"Guaraldi and colleagues have produced a concise review of ageing and HIV infection. ... The focus of HIV care is shifting from immunodeficiency and opportunistic infections to age-related comorbidities. This informative resource allows practitioners in the field of HIV infection to familiarize themselves with current thinking in this area." (Frank Post, British Journal of Hospital Medicine, Vol. 77 (9), September, 2016)
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