Mass Spectrometry in the Biological Sciences: A Tutorial

I: Instrumentation for Mass Analysis and Detection.- 1. Sectors and Tandem Sectors.- 2. Hybrid Tandem Mass Spectrometry.- 3. Triple Quadrupole Mass Spectrometry.- 4. Quadrupole Ion Trap Mass Spectrometers for Studies of Biomolecules.- 5. Fourier Transform Mass Spectrometry: Features, Principles, Capabilities, and Limitations.- 6. Time-of-Flight Mass Spectrometers.- 7. Ion Detection in Mass Spectrometry.- II: Methods in Mass Spectrometry.- 8. Electrospray Mass Spectrometry.- 9. Laser Desorption Mass Spectrometry. Part I: Basic Mechanisms and Techniques.- 10. Laser Desorption Mass Spectrometry. Part II: Performance and Applications of Matrix-Assisted Laser Desorption/Ionization of Large Biomolecules.- 11. Laser Desorption, Chemical Ionization, and Laser Desorption/Chemical Ionization Applications with Fourier Transform Mass Spectrometry.- 12. Plasma Desorption Mass Spectrometry: Principles and Applications to Protein Studies.- 13. Continuous Flow Fast Atom Bombardment Mass Spectrometry in Analytical Biochemistry.- 14. Combined Liquid Chromatography/Mass Spectrometry (LC/MS): A Review.- 15. Combined Supercritical Fluid Chromatography/Mass Spectrometry (SFC/MS).- 16. Determination of Biomolecules by Using Liquid Chromatography and Thermospray Mass Spectrometry: from Penicillins to Peptides.- 17. Neutralization-Reionization Mass Spectrometry: Fundamental Studies and Analytical Applications.- 18. Some Applications of the Quantum-Mechanical Semiempirical Methods to the Gas-Phase Chemistry of Bio-Organic Ions.- III: Applications to Biomolecules.- 19. Characterization of Human Hemoglobin Variants by Mass Spectrometry.- 20. Detection of Post-Translational Modification of Proteins by Mass Spectrometry.- 21. Manipulation of Experimental Variables for FAB MS and MS/MS to Facilitate Identification of a Post-Translational Modification in Rabbit Elongation Factor l?.- 22. Use of FAB MS and MS/MS in the Structural Determinations of Cockroach Neuropeptides.- 23. The Mass

`I therefore can be highly recommended to all chemists and physicist who are interested to learn about the current applicability of mass spectrometry to biological sciences and in particular to those who are practising this area of research.' Recueil dex Travaux Chimiques des Pays-Bas 'In conclusion, Mass Spectrometry in the sciences: A Tutorial achieves its objective as a tutorial for biological mass spectrometry. This book would be an excellent complement to an introductory mass spectrometry book because it contains the most recent techniques...covered by most introductory texts....I recommend this book as an ideal primer to understanding the current status of biological mass spectrometry' 'Applied Spectroscopy' 46:10 1992