Mass Spectrometry
Instrumentation, Interpretation, and Applications
(Sprache: Englisch)
Helps students fully leverage mass spectrometry in whichever field of research they choose
Mass Spectrometry: Instrumentation, Interpretation, and Applications enables students to become fully versed in the principles and uses of mass spectrometry....
Mass Spectrometry: Instrumentation, Interpretation, and Applications enables students to become fully versed in the principles and uses of mass spectrometry....
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Helps students fully leverage mass spectrometry in whichever field of research they chooseMass Spectrometry: Instrumentation, Interpretation, and Applications enables students to become fully versed in the principles and uses of mass spectrometry. Featuring contributions from international experts, the text introduces the many perspectives and approaches that different scientific fields bring to mass spectrometry, including applications for organic and inorganic chemistry, forensic science, biotechnology, and much more. This multidisciplinary approach enables students to apply their knowledge in their chosen fields of research in order to identify, quantify, and determine the structures and chemical properties of compounds.
This text is divided into three parts that guide students from basic principles to applications:
* Part One, Instrumentation, begins with basic definitions and explanations followed by a discussion of the mass spectrometer and its building blocks. Next, the text describes fragmentation methods and tandem MS analyzer configurations, ending with a short summary of separation methods used in conjunction with mass spectrometry.
* Part Two, Interpretation, explains basic concepts in mass spectra interpretation and then demonstrates how these concepts are used to interpret mass spectra in organic chemistry. Students also learn how to use mass spectrometry as a tool for peptide sequencing and how to optimize sensitivity and specificity in mass spectrometric proteome analysis.
* Part Three, Applications, features ten researchers and research groups from different fields describing how they use mass spectrometry in their own work.
Designed for graduate-level students, this textbook assumes that most students will not become mass spectrometry specialists. Instead, it focuses on how they can use the mass spectrometer to support and advance research across a broad range of disciplines.
Helps students fully leverage mass spectrometry in whichever field of research they choose
Mass Spectrometry: Instrumentation, Interpretation, and Applications enables students to become fully versed in the principles and uses of mass spectrometry. Featuring contributions from international experts, the text introduces the many perspectives and approaches that different scientific fields bring to mass spectrometry, including applications for organic and inorganic chemistry, forensic science, biotechnology, and much more. This multidisciplinary approach enables students to apply their knowledge in their chosen fields of research in order to identify, quantify, and determine the structures and chemical properties of compounds.
This text is divided into three parts that guide students from basic principles to applications:
- Part One, Instrumentation, begins with basic definitions and explanations followed by a discussion of the mass spectrometer and its building blocks. Next, the text describes fragmentation methods and tandem MS analyzer configurations, ending with a short summary of separation methods used in conjunction with mass spectrometry.
- Part Two, Interpretation, explains basic concepts in mass spectra interpretation and then demonstrates how these concepts are used to interpret mass spectra in organic chemistry. Students also learn how to use mass spectrometry as a tool for peptide sequencing and how to optimize sensitivity and specificity in mass spectrometric proteome analysis.
- Part Three, Applications, features ten researchers and research groups from different fields describing how they use mass spectrometry in their own work.
Designed for graduate-level students, this textbook assumes that most students will not become mass spectrometry specialists. Instead, it focuses on how they can use the mass spectrometer to support and advance research across a broad range of disciplines.
Mass Spectrometry: Instrumentation, Interpretation, and Applications enables students to become fully versed in the principles and uses of mass spectrometry. Featuring contributions from international experts, the text introduces the many perspectives and approaches that different scientific fields bring to mass spectrometry, including applications for organic and inorganic chemistry, forensic science, biotechnology, and much more. This multidisciplinary approach enables students to apply their knowledge in their chosen fields of research in order to identify, quantify, and determine the structures and chemical properties of compounds.
This text is divided into three parts that guide students from basic principles to applications:
- Part One, Instrumentation, begins with basic definitions and explanations followed by a discussion of the mass spectrometer and its building blocks. Next, the text describes fragmentation methods and tandem MS analyzer configurations, ending with a short summary of separation methods used in conjunction with mass spectrometry.
- Part Two, Interpretation, explains basic concepts in mass spectra interpretation and then demonstrates how these concepts are used to interpret mass spectra in organic chemistry. Students also learn how to use mass spectrometry as a tool for peptide sequencing and how to optimize sensitivity and specificity in mass spectrometric proteome analysis.
- Part Three, Applications, features ten researchers and research groups from different fields describing how they use mass spectrometry in their own work.
Designed for graduate-level students, this textbook assumes that most students will not become mass spectrometry specialists. Instead, it focuses on how they can use the mass spectrometer to support and advance research across a broad range of disciplines.
Inhaltsverzeichnis zu „Mass Spectrometry “
FOREWORDCONTRIBUTORS
PART I INSTRUMENTATION
1 DEFINITIONS AND EXPLANATIONS (Ann Westman-Brinkmalm and Gunnar Brinkmalm)
References
2 A MASS SPECTROMETER'S BUILDING BLOCKS (Ann Westman-Brinkmalm and Gunnar Brinkmalm)
References
3 TANDEM MASS SPECTROMETRY (Ann Westman-Brinkmalm and Gunnar Brinkmalm)
References
4 SEPARATION METHODS (Ann Westman-Brinkmalm, Jerzy Silberring, and Gunnar Brinkmalm)
References
PART II INTERPRETATION
5 INTRODUCTION TO MASS SPECTRA INTERPRETATION: ORGANIC CHEMISTRY (Albert T. Lebedev)
References
6 SEQUENCING OF PEPTIDES AND PROTEINS (Marek Noga, Tomasz Dylag, and Jerzy Silberring)
Acknowledgments
References
Online Tutorials
7 OPTIMIZING SENSITIVITY AND SPECIFICITY IN MASS SPECTROMETRIC PROTEOME ANALYSIS (Jan Eriksson and David Fenyö)
References
PART III APPLICATIONS
8 DOPING CONTROL (Graham Trout)
References
9 OCEANOGRAPHY (R. Timothy Short, Robert H. Byrne, David Hollander, Johan Schijf, Strawn K. Toler, and Edward S. VanVleet)
References
10 "OMICS" APPLICATIONS (Simone Koñig)
11 SPACE SCIENCES (Robert Sheldon)
References
12 BIOTERRORISM (Vito G. DelVecchio and Cesar V. Mujer)
References
13 IMAGING OF SMALL MOLECULES (MaBgorzata Iwona Szynkowska)
References
14 UTILIZATION OF MASS SPECTROMETRY IN CLINICAL CHEMISTRY (Donald H. Chace)
15 POLYMERS (Maurizio S. Montaudo)
References
16 FORENSIC SCIENCES (Maria Kala)
References
17 NEW APPROACHES TO NEUROCHEMISTRY (Jonas Bergquist, Jerzy Silberring, and Rolf Ekman)
Acknowledgments
References
PART IV APPENDIX
INDEX
Autoren-Porträt von Dominic M. Desiderio, Nico M. Nibbering
Rolf Ekman, PhD, is a Professor of Neurochemistry at University of Gothenburg in Sweden.JERZY SILBERRING, PhD, is the Head of the Department of Neurobiochemistry in the Department of Chemistry and the former deputy head of the Regional Laboratory of Physicochemical Analyses at Jagiellonian University in Krakow, Poland.
Ann M. Westman-Brinkmalm, PhD, is a Junior Research Fellow at the Sahlgrenska Academy at University of Gothenburg in Sweden.
Agnieszka Kraj, PhD, is an Assistant Professor in the Department of Neurobiochemistry, Faculty of Chemistry at Jagiellonian University in Krakow, Poland.
Bibliographische Angaben
- Autoren: Dominic M. Desiderio , Nico M. Nibbering
- 2009, 1. Auflage, 400 Seiten, Maße: 16,1 x 24,2 cm, Gebunden, Englisch
- Herausgegeben: Rolf Ekman, Jerzy Silberring, Ann M. Westman-Brinkmalm
- Verlag: Wiley & Sons
- ISBN-10: 0471713953
- ISBN-13: 9780471713951
- Erscheinungsdatum: 30.04.2009
Sprache:
Englisch
Pressezitat
"It was my great pleasure to read this clearly written and well organized mass spectrometry (MS) book. In view, it can serve as an excellent textbook for both undergraduate and graduate students who major in analytical, biological, forensic, or environmental chemistry, as well as a valuable resource to those researchers who are interested in the MS-based chemical analysis." (J Am Soc Mass Spectrom, 2011)"The book is particularly designed for graduate students, with the assumption being made that most of them will not become mass spectrometry specialists. Instead, it focuses on how they can use the technique to support and advance research across a broad range of disciplines." (Chemistry Journals, 11 April 2011)
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