Mathematical Modeling in Microbial Ecology

1. What is Happening to Microbial Ecology?.- 1. Introduction.- 2. Analytical Methods.- 3. Kinetic Aspects.- 4. Principles of Kinetic Modeling.- 5. Progress in Statistical Methods.- 6. Conclusions.- 2. Modeling Microbial Processes: An Overview of Statistical Considerations.- 1. Introduction.- 2. Model Identification versus Discrimination.- 3. The Least-Squares Criterion.- 4. Model Identification.- 5. Model Discrimination.- 6. Optimal Experiments for Parameter Estimation.- 7. Concluding Remarks.- References.- 3. Analysis of Repeated Measures Data Using Nonlinear Models.- 1. Introduction.- 2. The Model.- 3. Parameter Estimation.- 4. Comparing the Treatments.- 5. Constructing Confidence Bands for the Models.- 6. Example 1: Growing Cookies.- 7. Example 2: Cumulative Radioactive CO2 Production.- 8. Summary.- References.- 4. The Monod Model and Its Alternatives.- 1. Jacques Monod: His Life and Work.- 2. The Monod Model and Its Derivations.- 3. Limitation of the Hyperbolic Model.- 4. The Blackman (1905) Model and the Best (1955) Model.- 5. Still More Complication: The Phosphotransferase System.- 6. Still More Complications: The Kinetic Contribution of Porins and Passage through the Outer Membrane.- 7. The Experimental Measurement of Glucose Consumption.- 8. Selection of a Mutant Growing More Avidly at Low Glucose Concentrations.- 9. The Data Fitting: The Role of Models.- 10. The Statistical Fitting.- 11. Diffusion Limitation and Effect of Multiple Layers.- 12. The Effect of the Variation of the Surface Area to Volume during the Cell Cycle.- 13. Grave Omissions.- 14. Conclusions.- References.- 5. Using Transport Model Interpretations of Tracer Tests to Study Microbial Processes in Groundwater.- 1. Introduction.- 2. The Groundwater Environment.- 3. Measuring Microbial Processes in an Aquifer.- 4. Tracer-Test Technology.- 5. Transport-Process Models.- 6. Assessing Methane Oxidation.- 7. Assessing Denitrification.- 8. Future Applications and Limitations.- References.- 6.