Molecular Mechanisms of Werner's Syndrome
(Sprache: Englisch)
During our short time on earth, we all undergo the highly complex process of aging, and with it, we experience the many physiological symptoms. Studies of premature aging have produced a great deal of information that gives some aspects of aging a better...
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Klappentext zu „Molecular Mechanisms of Werner's Syndrome “
During our short time on earth, we all undergo the highly complex process of aging, and with it, we experience the many physiological symptoms. Studies of premature aging have produced a great deal of information that gives some aspects of aging a better understanding. This book explores Werner's syndrome. To some, Werner's syndrome is considered a caricature of aging, but others will find it fascinating that only one mutated human gene (WRN) can bring about a multitude of complicated phenotypes that are usually associated with aging.
Inhaltsverzeichnis zu „Molecular Mechanisms of Werner's Syndrome “
1. Clinical Aspects of Werner's Syndrome: Its Natural History and the Genetics of the Disease.- 2. Biochemical Roles of RecQ Helicases.- 3. Biochemical Characterization of the Werner Syndrome DNA Helicase-Exonuclease.- 4. Proteins That Interact with the Werner Syndrome Gene Product.- 5. Sensitivity of Werner's Syndrome Cells to DNA Damaging Agents: Insights into the Biological Functions of the Werner Protein.- 6. Yeast RecQHelicases: Clues to DNA Repair, Genome Stability and Aging.- 7. Potential Function of the Werner's Syndrome Homologue in the African Clawed Frog and the Mouse.- 8. Proposed Biological Functions for the Werner Syndrome Protein in DNA Metabolism.- Replicative Senescence, Telomeres and Werner's Syndrome.
Bibliographische Angaben
- Autor: Michel Lebel
- 2012, X, 156 Seiten, Maße: 23,4 cm, Kartoniert (TB), Englisch
- Verlag: Springer, Berlin
- ISBN-10: 1461347661
- ISBN-13: 9781461347668
Sprache:
Englisch
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