NFX1
(Sprache: Englisch)
Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Transcriptional repressor NF-X1 is a protein that in humans is encoded by the NFX1 gene. MHC class II gene expression is...
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Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. Transcriptional repressor NF-X1 is a protein that in humans is encoded by the NFX1 gene. MHC class II gene expression is controlled primarily at the transcriptional level by transcription factors that bind to the X and Y boxes, two highly conserved elements in the proximal promoter of MHC class II genes. The protein encoded by this gene is a transcriptional repressor capable of binding to the conserved X box motif of HLA-DRA and other MHC class II genes in vitro. The protein may play a role in regulating the duration of an inflammatory response by limiting the period in which class II MHC molecules are induced by IFN- . Three alternative splice variants, each of which encodes a different isoform, have been identified.
Bibliographische Angaben
- 2010, 104 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Herausgegeben von Surhone, Lambert M.; Tennoe, Mariam T.; Henssonow, Susan F.
- Verlag: Betascript Publishing
- ISBN-10: 6131346534
- ISBN-13: 9786131346538
Sprache:
Englisch
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