Pathogenesis of Periodontal Diseases

Periodontal Pathogenesis: Introduction and Definitions.- Diversity of the Oral Microbiome in Periodontal Health and Disease.- Subgingival Biofilms as Etiological Factors of Periodontal Diseases.- Bacterial Virulence Factors that Contribute to Periodontal Pathogenesis.- Central Role of Neutrophils in Periodontal Pathogenesis.- Active Matrix Metalloproteinase 8 - Contributor to Periodontitis and a Missing Link between Dentistry and Medicine.- Inflammatory Pathways of Bone Resorption in Periodontitis.- Genetic Influences on the Periodontal Microbial-Host Cross-Talk.- Antimicrobial Peptides: Roles in Periodontal Health and Disease.- Periodontal Pathogenesis: Conclusions and Future Directions.

Prof. Bostanci is dually qualified with a Dental degree (Ege University, Izmir, Turkey, 1999) and a PhD in Periodontology (University of London, UK, 2007). She also received advanced clinical training in Periodontology (Ege University, Izmir and Eastman Dental Institute, London). In 2007-2008, she worked as Clinical Lecturer at the Centre for Clinical and Diagnostic Oral Sciences, Barts and the London Dental Institute, QMUL. In 2008-2009 she attained a Walport Clinical Academic Lectureship funded by the National Institute of Health Research (NIHR), at the Division of Periodontology, UCL Eastman Dental Institute, London, UK. From 2009 until 2016 she was Principal Investigator at the Institute of Oral Biology, Center of Dental Medicine of the University of Zürich, Switzerland. In 2013 she attained her Habilitation (Venia Legendi) in Oral Biology and Periodontology. She has received distinguished scientific awards in her field, including the Sir Wilfred Fish Price of the BritishSociety of Periodontology, the Philips Oral Healthcare Young Investigator Research Prize and the Sigmund Socransky Young Investigator Award of the International Association for Dental Research (IADR). She is Associate Editor for BMC Oral Health and Editorial Board member for Oral Health and Preventive Dentistry, and Frontiers of Cellular and Infection Microbiology. Her work is a great example of incorporation of basic sciences into clinical research, focusing on the investigation of various molecular biomarkers of disease in biological samples (including oral tissue, gingival crevicular fluid, serum and saliva). Hence, her special research interests span from diagnostic and prognostic molecular markers for periodontal diseases, to the impact of oral health on general health. She is currently Professor of Inflammation Research specializing in Periodontics, at the Department of Dental Medicine, Karolinska Institute, Sweden.

Prof. Belibasakis studied Dentistryat the Aristotle University of