RAS Family GTPases
(Sprache: Englisch)
Since 1982, Ras proteins have been the subject of intense research investigation by the biomedical research community. The wide interest in Ras has been stimulated for three key reasons. This book features chapters contributed by leading investigators in...
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Klappentext zu „RAS Family GTPases “
Since 1982, Ras proteins have been the subject of intense research investigation by the biomedical research community. The wide interest in Ras has been stimulated for three key reasons. This book features chapters contributed by leading investigators in the field that highlight the current state-of-the art in Ras biochemistry, structure and biology. This book is an excellent reference for students in the biomedical sciences and for investigators in the field.
Inhaltsverzeichnis zu „RAS Family GTPases “
1. Ras-GEFs and Ras GAPs2. Structural Principles of Ras Interaction with Regulators and Effectors
3. Ras and the Raf/MEK/ERK cascade
4. Noncanonical effector targets of oncogenic Ras protein
5. Effectors of Ras-mediated oncogenesis
6. Rho proteins in Ras signaling and transformation
7. Global effects of Ras signaling on the genetic program in mammalian cells
8. Ras Signaling In C. elegans Ras: a genetic overview
9. Ras family G-proteins in S. cerevisiae and S. pombe
10. Comparison of the effects of Ras effector mutants and Ras effectors on transformed and tumorigenic growth of human and rodent cells
11. Genetically engineered mice harboring ras mutations as models of human cancer: in media Ras
12. Ras family proteins (Rap, Ral, R-Ras, Rheb, Rit/Rin, and others)
13. k B-Ras: a small GTPase that influences NF-k B signaling
14. Anti-Ras approaches and cancer treatment
Bibliographische Angaben
- 2006, 2006, 397 Seiten, Maße: 16 x 24,1 cm, Gebunden, Englisch
- Herausgegeben:Der, Channing
- Herausgegeben: Channing Der
- Verlag: Springer Netherlands
- ISBN-10: 1402043287
- ISBN-13: 9781402043284
- Erscheinungsdatum: 13.09.2006
Sprache:
Englisch
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