Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology
Scientific and Clinical Aspects of Anemia in Cancer
(Sprache: Englisch)
Anemia, a frequent complication of cancer and its treatments, produces unwanted symptoms and significantly impairs metabolic and physiologic functions, as well as patients' activity, quality of life and even life expectancy. In its new Second Edition, this...
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Anemia, a frequent complication of cancer and its treatments, produces unwanted symptoms and significantly impairs metabolic and physiologic functions, as well as patients' activity, quality of life and even life expectancy. In its new Second Edition, this book presents current knowledge on anemia in cancer and its treatment with Recombinant Human Erythropoietin (rhEPO). Expanded, updated and newly added chapters describe scientific and clinical aspects of anemia, and give diagnostic and therapeutic recommendations on use of rhEPO. This is an essential source of information for radiotherapists, medical oncologists, hematologists, internists, pediatricians, surgeons, specialists in transfusion and laboratory medicine, and pharmacologists.
Klappentext zu „Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology “
Anemia, a frequent complication of cancer and its treatments, produces unwanted symptoms and significantly impairs metabolic and physiologic functions, as well as patients' activity, quality of life and even life expectancy. In its new Second Edition, this book presents current knowledge on anemia in cancer and its treatment with Recombinant Human Erythropoietin (rhEPO). Expanded, updated and newly added chapters describe scientific and clinical aspects of anemia, and give diagnostic and therapeutic recommendations on use of rhEPO. This is an essential source of information for radiotherapists, medical oncologists, hematologists, internists, pediatricians, surgeons, specialists in transfusion and laboratory medicine, and pharmacologists.
Inhaltsverzeichnis zu „Recombinant Human Erythropoietin (rhEPO) in Clinical Oncology “
- Physiology of erythropoiesis- Biology of EPO
- EPO and EPO-receptor expression in tumor cells and their functional role
- Classification and characterization of anemia in cancer
- Pathophysiology of cancer-related and chemotherapy-induced anemia
- Prevalence, incidence, and treatment of anemia in cancer patients
- Prognostic significance of anemia in cancer chemotherapy
- Incidence and impact of anemia in radiation oncology
- Relationship between anemia and tumor hypoxia
- Tumor hypoxia and therapeutic resistance
- Symptomatology of anemia
- Impact of anemia on organ functions
- Relationship of hemoglobin, fatigue, and quality of life in anemic cancer patients
- Red blood cell transfusions, risks and limitations
- Pharmacology, pharmacokinetics and safety of rhEPO
- rhEPO in anemia associated with multiple myeloma and non-Hodgkin lymphoma
- rhEPO in myeloid disorders
- rhEPO in anemia associated with solid tumors and chemotherapy
- Predictive factors for response of anemia to rhEPO.*
Bibliographische Angaben
- Autoren: Marcos Cruz , Marjan Colletti
- 2008, 2nd, rev. and enl. ed., 866 Seiten, Maße: 17,5 x 25 cm, Gebunden, Englisch
- Ed. by Mohammad R. Nowrousian
- Herausgegeben: Mohammad R. Nowrousian
- Verlag: Springer
- ISBN-10: 3211252231
- ISBN-13: 9783211252239
Sprache:
Englisch
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