Sickle Cell Disease and Hematopoietic Stem Cell Transplantation

Clinical Manifestations of Sickle Cell Disease Across the Lifespan.- Pathobiology of Sickle Cell Disease Vaso-Occlusion and Targeted Therapies.- Current Non-HSCT Related Treatments for SCD.- Risk Based Therapies for Sickle Cell Disease.- Transfusion Support of the Patient with Sickle Cell Disease Undergoing Transplantation.- Neurological Manifestations of Sickle Cell Disease and Their Impact on Allogeneic Hematopoietic Stem Cell Transplantation.- Overview of Hematopoietic Stem Cell Transplantation for Non-Malignant Diseases.- Unique Challenges of Hematopoietic Stem Cell Transplant for Sickle Cell Disease.- The Ethics of Hematopoietic Stem Cell Transplantation for Sickle Cell Disease.- Psychosocial Care and Education of Children with Sickle Cell Disease undergoing Hematopoietic Stem Cell Transplant and their Families.- Long Term Effects of Hematopoietic Stem Cell Transplantation for Sickle Cell Disease.- Matched Sibling Donor Hematopoietic Stem Cell Transplantation for Sickle Cell Disease.- Unrelated Donor Hematopoietic Stem Cell Transplantation for Sickle Cell Disease.- Haploidentical Hematopoietic Cell Transplantation for Sickle Cell Disease.- Gene Therapy 101: The Path Toward Becoming a Realistic Cure for Patients with Sickle Cell Disease.

Emily Riehm Meier, MD, MSHS
Pediatric Hematologist and Director, Sickle Cell Research, Indiana Hemophilia and Thrombosis Center, Indianapolis, IN, USA
Allistair Abraham, MDChildren's National Medical Center, Division of Blood and Marrow Transplantation, Washington, DC, USA
Ross M. Fasano, MDEmory University School of Medicine, Department of Pathology & Laboratory Medicine, Atlanta GA, USA

"An authoritative work on hematopoietic stem cell transplantation (HSCT) ... . Written by leading expert clinicians and researchers ... . this is a very valuable resource for clinicians and scientists dealing with this devastating disease and pursuing a curative therapy." (Ravi Salgia, Doody's Book Reviews, August, 2018)