Structure and Function in Cell Signalling
(Sprache: Englisch)
Incorporating the many recent developments in the field, Structure and Function in Cell Signalling is a concise and accessible introduction to the dynamic field of signal transduction. The book demystifies cell signaling through a nuts and bolts approach by...
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Incorporating the many recent developments in the field, Structure and Function in Cell Signalling is a concise and accessible introduction to the dynamic field of signal transduction. The book demystifies cell signaling through a nuts and bolts approach by illustrating the way signaling pathways are made up from common components.
Klappentext zu „Structure and Function in Cell Signalling “
Structure and Function in Cell Signalling is a concise and accessible introduction to the dynamic but complex field of signal transduction. Rather than simply cataloguing all signalling molecules and delineating every known pathway, this book aims to break signalling down into common elements and activities - the 'nuts and bolts' of cellular information exchange.With an emphasis on clarity of presentation throughout, the book teaches the basic principles focusing on a mature core of knowledge, providing students with a foundation of learning in this complex and potentially confusing subject. It also addresses the issue of variation in the numbering of key amino acids as well as featuring interaction with RasMol software, and exercises to aid understanding.
Structure and Function in Cell Signalling is a concise and accessible introduction to the dynamic but complex field of signal transduction. Rather than simply cataloguing all signalling molecules and delineating every known pathway, this book aims to break signalling down into common elements and activities - the 'nuts and bolts' of cellular information exchange.
An accessible introduction to the complex field of cell signalling.
Interacts with RasMol software - freely downloadable for viewing structures in 3D.
Includes exercises and clear instructions in the use of RasMol.
Well illustrated in full colour throughout.
Structure and Function in Cell Signalling will prove invaluable to students across a range of life science degree programmes including biochemistry, cell and molecular biology, physiology, biomedicine and oncology. This book will provide a clear, accessible introduction to this rapidly expanding field.
Incorporating the many recent developments in the field, Structure and Function in Cell Signalling is a concise and accessible introduction to the dynamic field of signal transduction. The book demystifies cell signalling through a nuts and bolts approach by illustrating the way signalling pathways are made up from common components. This active learning approach helps readers to understand and apply their knowledge. The book addresses the issue of variation in the numbering of key amino acids and features an accompanying website, interaction with RasMol (molecular rendering software), and exercises to aid understanding.
- An introductory text that carefully explains the basic principles with the latest developments
- Shows how signalling pathways are made up from common components to help simplify this complex subject
- Accompanying website features schematic representations and animations of mechanisms
- Interaction with RasMol, molecular rendering software
- Includes a glossary of multiple terms for genes that includes derivation of acronyms and exercises to aid understanding
- Takes full advantage of the recent high definition x-ray crystal structures of the important proteins and complexes
- An introductory text that carefully explains the basic principles with the latest developments
- Shows how signalling pathways are made up from common components to help simplify this complex subject
- Accompanying website features schematic representations and animations of mechanisms
- Interaction with RasMol, molecular rendering software
- Includes a glossary of multiple terms for genes that includes derivation of acronyms and exercises to aid understanding
- Takes full advantage of the recent high definition x-ray crystal structures of the important proteins and complexes
Inhaltsverzeichnis zu „Structure and Function in Cell Signalling “
AcknowledgmentsPreface
1 The components and foundations of signalling
References
2 Enzymes and receptors - quantitative aspects
References
3 Modules and motifs in transduction
References
4 Protein kinase enzymes - activation and auto-inhibition
References
5 7-pass receptors and the catabolic response
References
6 Single pass growth factor receptors
References
7 G proteins (I) - monomeric G proteins
References
8 G proteins (II) - heterotrimeric G proteins
References
9 The insulin receptor and the anabolic response
References
10 Mitogens and cell cycle progression
References
Appendix 1: Worked examples
Appendix 2: RasMol: installation and use
Index
Bibliographische Angaben
- Autor: John D. Nelson
- 2008, 1. Auflage., 416 Seiten, Maße: 16,5 x 23,9 cm, Kartoniert (TB), Englisch
- Verlag: Wiley & Sons
- ISBN-10: 0470025514
- ISBN-13: 9780470025512
Sprache:
Englisch
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