Synthesis of New 1,2,3,4 - TetrahydroquInazoline Derivatives
Synthesis of New Substitute of Anticancer Agent. Part II
(Sprache: Englisch)
1,2,3,4-Tetrahydroquinazoline is an important scaffold due to variety of pharmacological properties associated with the derivatives bearing this heterocyclic. Especially their importance in the cancer chemotherapy is unparallel. In our efforts to discover...
Leider schon ausverkauft
versandkostenfrei
Buch
54.90 €
27 DeutschlandCard Punkte
sammeln
- Lastschrift, Kreditkarte, Paypal, Rechnung
- Kostenlose Rücksendung
- Ratenzahlung möglich
Produktdetails
Produktinformationen zu „Synthesis of New 1,2,3,4 - TetrahydroquInazoline Derivatives “
Klappentext zu „Synthesis of New 1,2,3,4 - TetrahydroquInazoline Derivatives “
1,2,3,4-Tetrahydroquinazoline is an important scaffold due to variety of pharmacological properties associated with the derivatives bearing this heterocyclic. Especially their importance in the cancer chemotherapy is unparallel. In our efforts to discover new chemical pharmacophore which may lead to formation of new anticancer agent. The essence of work is to synthesize different substituted tetrahydroquinazoline fused with substituted benzo[d]isothiazol-3(2H)-one and to test them for their anticancer activity in vitro. Novel compounds as potent inhibitors of EGF receptor tyrosine kinase inhibitors. In the light of above, 3rd position of tetrahydroquinazoline ring were explored to obtain different derivatives. The reaction was monitored by Thin Layer Chromatography (TLC) using suitable mobile phase. The Rf values were compared and determined the Melting Point (MP) of derivatives. It is found that they were different from each other's. Further, these derivatives were characterizedand confirmed by IR, 1H-NMR, 13C-NMR, and Mass spectral studies.
Autoren-Porträt von Mariya Aaraf, Parin S. Sidat, M. N. Noolvi
Aaraf, MariyaMiss Mariya Hidayat Aaraf is working as Assistant Professor in Department of Pharmaceutical Chemistry at Shree Dhanvantary Pharmacy College, Kim, Surat, Gujarat. She has completed M Pharm in Pharmaceutical Chemistry from Gujarat Technological University, Ahmadabad. She has 2 years' experience in Synthetic Chemistry as well as Cancer Research.
Bibliographische Angaben
- Autoren: Mariya Aaraf , Parin S. Sidat , M. N. Noolvi
- 2019, 108 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 6200278989
- ISBN-13: 9786200278982
Sprache:
Englisch
Kommentar zu "Synthesis of New 1,2,3,4 - TetrahydroquInazoline Derivatives"
0 Gebrauchte Artikel zu „Synthesis of New 1,2,3,4 - TetrahydroquInazoline Derivatives“
| Zustand | Preis | Porto | Zahlung | Verkäufer | Rating |
|---|
Schreiben Sie einen Kommentar zu "Synthesis of New 1,2,3,4 - TetrahydroquInazoline Derivatives".
Kommentar verfassen