The Autoimmune Fix

pathogenic autoimmunity. The benefit of understanding this spectrum is so we can consciously shift our direction away from disease and back to vibrant health. That is the purpose of this book.

This health deterioration can be measured in terms of its intensity by the level of antibodies. When there is a slight elevation of antibodies, some people may have noticeable symptoms, while others with tremendously high levels of antibodies may have no symptoms at all. Yet both types of people are on the spectrum, and they will progress along the spectrum until they are diagnosed with a chronic or deadly disease. This is why it does not matter whether you notice symptoms or not: If you have elevated antibodies, they are fueling tissue degeneration.

Whenever we are exposed to any environmental trigger (such as gluten, peanuts, mold . . .), our immune system is activated to protect us. This is happening 24/7, and it's designed to work in the background so we don't notice it. This is referred to as normal immunity: You feel nothing. If the level of insult (the amount of exposure) increases, you might experience some kind of mild irritation, like a runny nose, sore muscles, or brain fog. If the level of exposure continues to increase, the immune system has to respond more aggressively, which begins the inflammatory cascade. Excess inflammation beyond the normal range will cause cellular damage. Continued cellular damage will cause tissue damage. Continued tissue damage will cause organ inflammation. Continued organ inflammation will increase the intensity of symptoms, and you develop elevated antibodies to that organ. Continued elevated antibodies to an organ leads to organ damage. Now you have symptoms that can be identified as an autoimmune disease.

This mechanism is the primary pathway in the development of autoimmune disease, opposite.

In 2003, Melissa Arbuckle, MD, PhD, and her colleagues published a landmark study in the New England J

best efforts to balance hormones, stabilize thyroid function, reduce stress, or almost any effort to get healthier. Read The Autoimmune Fix. You ll look back years from now and be grateful that you did. Dr. Tom O Bryan has done an outstanding job describing the autoimmune spectrum, why it matters, and how to identify if you re on the autoimmune spectrum. You'll save yourself unnecessary suffering by learning this information years before the damage is severe enough to cause symptoms.
--Sara Gottfried, MD, New York Times bestselling author of The Hormone Cure and The Hormone Reset Diet

No one gets an autoimmune disease overnight, whether it s MS, Rheumatoid Arthritis, Alzheimer s,... Scientists know that these diseases are decades-long processes of slow tissue damage with several distinct steps along the way before there s enough damage to warrant a diagnosis.

Dr. Tom O Bryan has done a remarkable job putting together a clear picture of what autoimmune diseases are, why the immune system begins attacking itself, and most importantly what you can do about it. His protocols are highly aligned with The Wahls Protocol. This book will change your life.
--Terry Wahls, MD, bestselling author of The Wahls Protocol

The field of autoimmunity is complex and ever expanding. Although there is much to learn, on going research continues to give us a clearer understanding of some of the vulnerabilities and triggers we face today. Dr. O'Bryan's book, The Autoimmune Fix, does a very good job of explaining some of the basic principles of how our diet and environmental exposures can activate our unique genes making us more vulnerable to developing an autoimmune disease. If this book helps you to avoid what may be triggers in your body to developing an autoimmune disease, it will have been time well-spent reading.
--Yehuda Shoenfeld, MD, FRCP, Head, Zabludowicz Center for Autoimmune Diseases, CHAIMSHEBA MEDICAL CENTER, Tel-Aviv University

"We are so thrilled to support Dr. O'Bryan's work,The Autoimmune Fix, a book whose time has come. Medicine is evolving and there is a new paradigm for preventing and reversing autoimmune disease, one that is empowering and surprisingly simple to implement. So thankful for this step-by-step manual out in the world to make it easy for anyone to take control of their health."
--James Maskell, Founder and CEO of Evolution of Medicine

"Dr. O'Bryan's information is always cutting edge and he is a brilliant clinician and author. His new book, The Autoimmune Fix, should be read by anyone suffering from autoimmunity. The information contained in the book can be life changing."
--Datis Kharrazian, DHSc, DC, FACN, CNS, Associate Clinical Professor Loma Linda University School of Medicine

"Dr. Tom O'Bryan is a pioneer in the field of clinical autoimmunity. His explanations of extremely sophisticated mechanisms into everyday language helps all of us to understand the path out of autoimmunity and into health. He's been holding the line for patients who have been misdiagnosed and has helped countless people over the years. If you're not feeling right, there's a chance you may be suffering from this hidden cause.This book is a must read!
--Pedram Shojai, OMD, Founder of Well.Org and New York Times bestselling author of The Urban Monk

The Autoimmune Fix is a must read. As a doctor who focuses onautoimmune thyroid disease, this is the most comprehensive evidence-basedoverview on autoimmune disease that I am aware of. The Autoimmune Fix can be areference manual for health care practitioners as well as a road map to guidepatients back to the health they deserve. Dr. O'Bryan masterfully integratesdecades of clinical experience, research, and training other physicians. Highlyrecommended!
--Alan Christianson, NMD New York Times bestselling author of The Adrenal Reset Diet

The hero who has contributed so much to the field of non-celiac gluten sensitivity and celiac disease now shines a light on a mysterious epidemic that is still in the shadows for many: autoimmune disease. Dr. O Bryan very elegantly connects the dots between environmental triggers such as food and how they can affect the very immune system that s supposed to protect us. THE AUTOIMMUNE FIX doesn t pull any punches. It unflinchingly identifies the foods that put you at risk for future autoimmune disease, foods you might love, foods you might think nothing about eating daily, but it also gives you actual detailed recipes and protocols that will have you eating and living your way to health. Dr. O Bryan also talks about predictive autoimmunity, one of my favorite subjects. With autoimmunity, you have two choices: wait until millions are suffering from full-blown autoimmune disorders, then put them on a lifetime of immune suppressants and biologics as well as years of suffering. Or, you can use predictive antibodies to detect autoimmunity in the early stages of the disease, and then take steps to halt or even reverse the course of the incipient autoimmune disorder. THE AUTOIMMUNE FIX wisely tells us to take the latter, more pro-active choice, and to paraphrase what Dr. O Bryan says in his book, it s not the doctors you see, the drugs you take, or the surgeries and therapies you undergo; what will impact your health ultimately are the choices you make in your life, and getting this book is one of those choices.
--Aristo Vojdani, PhD, MSc, CLS, CEO, Immunosciences Lab., Inc., and author of Neuroimmunity and the Brain-Gut Connection

"We are so thrilled to support Dr. O'Bryan's work, The Autoimmune Fix, a book whose time has come. Medicine is evolving and there is a new paradigm for preventing and reversing autoimmune disease, one that is empowering and surprisingly simple to implement. So thankful for this step-by-step manual out in the world to make it easy for anyone to take control of their health."
--James Maskell, Founder and CEO Evolution of Medicine

Dr. O Bryan's understanding of the physiopathology of autoimmune disease is second to none. His ability to translate complex research findings into practical, applicable recommendations that can be individualized to suit each patient s case is admirable. Because of his ability to make complexity accessible, translational and applicable, I recommend every nutrition practitioner to read Dr. O Bryan s book.
--Miguel Toribio-Mateas, MSC, BSC, NutMed, ABAAHP, FBANT, CNCH, Reg. Chairman of the British Association for Applied Nutrition and Nutritional Therapy


We allknow that an ounce of prevention is worth a pound of cure. Well, when you readthis book and implement Tom s advice you will be stacking the weights in yourfavour, helping yourself enjoy a healthier, longer life. Why? Because Dr. TomO Bryan has written a different kind of book here. He described how you canprevent auto-immunity from occurring in the first place. Fortune favours theprepared mind; now you have this book in your hand, don t let it go.
--Antony Haynes, Nutritional Therapist,Functional Medicine Practitioner, Author, Lecturer, Head of Technical Services,Nutri-Link, Ltd.


"Dr. Tom O'Bryan is one of the most important voices on autoimmunity in the wellness revolution. The information in this book can free millions who are locked in a quality of life that is less than they deserve. Brilliantly explained, backed by science, and a rock solid protocol to get your health back."
--Christa Orecchio, CN, HHC bestselling author of How to Conceive Naturally, Microbiome Expert


Dr O Bryan, does not just get the zeitgeist of immune dysfuntion as a primary driver of major degenerative illness, he helps to define it! A great narrative underpinned with relevant research served up with practical solutions ingest this, then switch your eating habits to those recommended; they will both have a profound effecton your health and life.
--Dr. Michael Ash, DO, ND, BSc, RNT, Managing Director & Head of Research and Development, Nutri-Link, Ltd.

During the past two decades, no single person has contributed more to the understanding and importance of recognizing the negative effects that Gluten has played in human health than Dr. Tom O Bryan. The hundreds of seminars, lectures and conferences where Dr. O Bryan has presented this breakthrough information to literally thousands of physicians is proven true by the results these physicians have experienced as they applied this knowledge to tens of thousandsof their patients. Dr. O Bryan s newbook The Autoimmune Fix will prove to become an essential tool to help assist the growing number of individuals whose health and lives are being impacted by the exposure to gluten on their immune system and quality of life. It is with gratitude and pride that I wish to offer my encouragement for everyone to get a copy of Dr. O Bryan s book as well as to each physician to also get a personal copy of this book and one for their waiting room as well.
--Tom Schembari, President, NuMedicaAdvancing Nutrition


"When new health information is identified, it can sometimes take a long time before doctors actually implement this information in their treatment protocols. I have had the privilege of working with Dr. Tom O'Bryan for more than a decade and admire his passion and commitment to pushing new health information to the forefront, supporting it with his own research and clinical experience, particularly to help other clinicians and patients identify possible triggers of autoimmune disease. The sooner these triggers are identified in a person, the higher the chance of arresting or reversing the disease development. A splendid job of explaining this difficult topic. You will be grateful you've read this."
--Jean Bellin, President, Cyrex Laboratories, Past President, Metagenics Nutrition

The hero who has contributed so much to the field of non-celiac gluten sensitivity and celiac disease now shines a light on a mysterious epidemic that is still in the shadows for many: autoimmune disease. Dr. O Bryan very elegantly connects the dots between environmental triggers such as food and how they can affect the very immune system that s supposed to protect us. The Autoimmune Fix doesn t pull any punches. It unflinchingly identifies the foods that put you at risk for future autoimmune disease, foods you might love, foods you might think nothing about eating daily, but it also gives you actual detailed recipes and protocols that will have you eating and living your way to health. Dr. O Bryan also talks about predictive autoimmunity, one of my favorite subjects. With autoimmunity, you have two choices: wait until millions are suffering from full-blown autoimmune disorders, then put them on a lifetime of immune suppressants and biologics as well as years of suffering. Or, you can use predictive antibodies to detect autoimmunity in the early stages of the disease, and then take steps to halt or even reverse the course of the incipient autoimmune disorder. The Autoimmune Fix wisely tells us to take the latter, more proactive choice, and to paraphrase what Dr. O Bryan says in his book, it s not the doctors you see, the drugs you take, or the surgeries and therapies you undergo; what will impact your health ultimately are the choices you make in your life, and getting this book is one of those choices.
--Aristo Vojdani, PhD, MSc, CLS, CEO of Immunosciences Lab., Inc., and author of Neuroimmunity and the Brain-Gut Connection

Dr. Tom O'Bryan's new book, The Autoimmune Fix, takes his readers down his path to "health enlightenment," which is a much deeper understanding of the underlying cause of disease and poor health. Dr. O'Bryan clearly lays out why individuals with certain genetic predispositions will react to certain foods, which will trigger inflammation that will lead to intestinal permeability and the start of a process which, if not checked, will trigger poor health, autoimmune diseases, or worse. More importantly, Dr. O'Bryan lays out how to avoid all this and regain your health using his two phases of transition, which are described in this book in great detail, and also include very helpful Transition Protocol Recipes to be used during his two phases of transition. I believe that anyone interested in living a healthier and longer life should read The Autoimmune Fix, including all doctors and health care practitioners, as it will lead all to a much greater understanding of health and disease.
--Scott Adams, Founder, www.Celiac.com

This is a fascinatingly detailed book about the outcome of autoimmunity its causes, mechanisms, and effects on the body. It tells you what to eat, and more importantly, what not to eat if you want to remain healthy, keep doing your marathon running and not be subject to the diseases caused by our affluent Westernised life-style and junk foods, and to which most of us are still prey. Read it and be enlightened! Warmly recommended for those worried about their bodies and brains .
--Professor Michael N. Marsh, Wolfson College, University of Oxford

As a doctor and brain scientist, I understand that autoimmune diseases pose one of the greatest threats to our bodies and our minds. Not only do they damage our organs, but they erode self-esteem and can be difficult to identify and treat. In this book, Tom O Bryan offers a sensitive and comprehensive account of autoimmune disease, all at once engaging us in both the reasons they occur, and what we can do about this. With the vast amount of information available, it s important to know where to look when you or a loved one needs help. Look no further! With the combination of the highest scientific integrity and the ease of understanding, this book is a gem worth getting and guarding, for it is bound to be regarded as a classic of its time.
--Srini Pillay, M.D. Assistant Professor, Harvard Medical School, Award-winning author of Life Unlocked

Dr. Tom O Bryan is brilliant at translating complex medical information into simple to understand ideas. In his new book, The Autoimmune Fix, he shows you a breakthrough plan to stop auto-immune triggers and restore your health. If you have an autoimmune disease, I urge you to read this book.
Steven Masley, MD, FAHA, FACN, FAAFP, CNS bestselling author of The 30-Day Heart Tune-Up and Smart Fat

I love this book! It was truly hard to put down. A fascinating read from one of the most brilliant men I know. This book is easy to read and holds your interest the whole way through. Thanks,Tom, I'm so proud of you. You're such a gift to the world. You nailed it!
--Donna Gates, International bestselling author of The Body Ecology Diet: Recovering Your Health and Rebuilding Your Immunity, and The Body Ecology Guide to Growing Younger

In my opinion, everyone should read this book. My colleague Dr. Tom O Bryan has been researching the serious progressive effects of the autoimmune spectrum for decades. He has gained incredible insights into its causes, effects, and how to vanquish the symptoms. This book contains his lifetime work. The concept of the autoimmune illness is complex to get your head around. However, Dr. O Bryan expertly explains it to us step-by-step so you can understand why your body is steadily deteriorating, and how to reverse this downward spiral. It is a progressive inflammatory state in your body that provokes your immune system to over respond and attack itself. He tells us that the three things necessary for the development of autoimmune disease are genetics, environmental triggers, and intestinal permeability: he explains this in easy-to-read detail. He tells us that it is the quantity and quality of our food that is important: he reveals that the stand-out culprits are gluten, dairy and sugar. Read this book and follow the steps to dampen down the fire of reactivity that can rage through your body.
--Prof. Rodney Ford MD, MBBS, FRACP, author of The Gluten Syndrome and Gluten: ZERO Global

"I can t recommend this book enough! The Autoimmune Fix is a must read for anyone who s frustrated going to doctor to doctor looking for answers to their chronic fatigue and inflammation, muscle and joint pain, digestive issues, neurological symptoms, memory and cognitive dysfunction and more. Dr. Tom O Bryan explains a very difficult subject in a very easy to read manner on the complexity of your immune system--how it can attack your own tissues, triggering symptoms and wreaking havoc to your body and brain health. Best of all, Dr. O Bryan provides a scientific and proven strategies on how fix it for good! Give yourself the gift of wellness and go through his "Transition Protocol." Each week you will notice your irritating symptoms just melting away one by one--improving your energy level and mental focus, minimizing your pain and inflammation, increasing your flexibility and strength, and so much more. The Autoimmune Fix is your roadmap to a lifetime of vibrant health!"
Dr. Susanne Bennett, #1 best-selling author of Mighty Mitoand The 7-Day Allergy Makeover and talk show host of Wellness for Life Radio on RadioMD and iHeart Radio