Tietz Textbook of Clinical Chemistry and Molecular Diagnostics

Section I: Principles of Laboratory Medicine

Introduction to Laboratory Medicine

Selection and Analytical Evaluation of Methods - With Statistical Techniques

Clinical Evaluation of Methods

Evidence Based Laboratory Medicine

Establishment and Use of Reference Values

Preanalytical Variables and Biological Variation

Specimen Collection and Processing

Quality Management
Section II: Analytical Techniques and Instrumentation

Principles of Basic Techniques and Laboratory Safety

Optical Techniques

Electrochemistry and Chemical Sensors

Electrophoresis

Chromatography and Extraction

Mass Spectrometry

Enzyme and Rate Analyses

Principles of Immunochemical Techniques

Nucleic Acid Techniques

Microfabrication and Microfluidics and Their Application to Clinical Diagnostics

Automation in the Clinical Laboratory

Point-of-Care Testing
Section III: Analytes

Amino Acids, Peptides, and Proteins

Serum Enzymes

Enzymes of the Red Blood Cell

Tumor Markers

Kidney Function Tests

Carbohydrates

Lipids, Lipoproteins, Apolipoproteins, and Other Cardiovascular Risk Factors

Electrolytes and Blood Gases

Hormones

Catecholamines and Serotonin

Vitamins and Trace Elements

Hemoglobin, Iron, and Bilirubin

The Porphyrias and Other Disorders of Porphyrin Metabolism

Therapeutic Drugs and Their Management

Clinical Toxicology

Toxic Metals
Section IV: Molecular Diagnostics and Genetics

Principles of Molecular Biology

Genomes and Nucleic Acid Alterations

Nucleic Acid Isolation

Inherited Diseases

Identity Assessment

Molecular Methods in Diagnosis and Monitoring of Infectious Diseases

Pharmacogenetics

Hematopoietic Malignancies

Plasma Nucleic Acids
Section V: Pathophysiology

Diabetes Mellitus

Cardiovascular Disease

Kidney Disease

Physiology and Disorders of Water, Electrolyte, and Acid-Base Metabolism

Liver Disease

Gastrointestinal and Pancreatic