Viral Vectors for Gene Therapy
Methods and Protocols
(Sprache: Englisch)
Viral Vectors for Gene Therapy: Methods and Protocols consists of 30 ch- ters detailing the use of herpes viruses, adenoviruses, adeno-associated viruses, simple and complex retroviruses, including lentiviruses, and other virus systems for vector...
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Viral Vectors for Gene Therapy: Methods and Protocols consists of 30 ch- ters detailing the use of herpes viruses, adenoviruses, adeno-associated viruses, simple and complex retroviruses, including lentiviruses, and other virus systems for vector development and gene transfer. Chapter cont- butions provide perspective in the use of viral vectors for applications in the brain and in the central nervous system. Viral Vectors for Gene Therapy: Methods and Protocols contains step-by-step methods for successful rep- cation of experimental procedures, and should prove useful for both experienced investigators and newcomers in the field, including those beginning graduate study or undergoing postdoctoral training. The "Notes" section contained in each chapter provides valuable troublesho- ing guides to help develop working protocols for your laboratory. With Viral Vectors for Gene Therapy: Methods and Protocols, it has been my intent to develop a comprehensive collection of modern molecular methods for the construction, development, and use of viral vectors for gene transfer and gene therapy. I would like to thank the many chapter authors for their contributions. They are all experts in various aspects of viral vectors, and I appreciate their efforts and hard work in developing comprehensive chapters. As editor, it has been a privilege to preview the development of Viral Vectors for Gene Therapy: Methods and Protocols, and to acquire insight into the various methodological approaches from the many different contri- tors.
Inhaltsverzeichnis zu „Viral Vectors for Gene Therapy “
Use of the Herpes Simplex Viral Genome to Construct Gene Therapy Vectors Edward A. Burton, Shaohua Huang, William F. Goins, and Joseph C. Glorioso Construction of Multiply Disabled Herpes Simplex Viral Vectors for Gene Delivery to the Nervous System Caroline E. Lilley and Robert S. Coffin
Improved HSV-1 Amplicon Packaging System Using ICP27-Deleted, Oversized HSV-1 BAC DNA Yoshinaga Saeki, Xandra O. Breakefield, and E. Antonio Chiocca
Herpes Simplex Amplicon Vectors Charles J. Link, Nicholas N. Vahanian, and Suming Wang
Strategies to Adapt Adenoviral Vectors for Targeted Delivery Catherine R. O'Riordan, Antonius Song, and Julia Lanciotti
Use of Recombinant Adenovirus for Gene Transfer into the Rat Brain: Evaluation of Gene Transfer Efficiency, Toxicity, and Inflammatory and Immune Reactions Andres Hurtado-Lorenzo, Anne David, Clare Thomas, Maria G. Castro, and Pedro R. Lowenstein
Generation of Adenovirus Vectors Devoid of All Virus Genes by Recombination Between Inverted Repeats Hartmut Stecher, Cheryl A. Carlson, Dmitry M. Shayakhmetov, and André Lieber
Packaging Cell Lines for Generating Replication-Defective and Gutted Adenoviral Vectors Jeffrey S. Chamberlain, Catherine Barjot, and Jeannine Scott
Improving the Transcriptional Regulation of Genes Delivered by Adenovirus Vectors Semyon Rubinchik, Jan Woraratanadharm, Jennifer Schepp, and Jian-yun Dong
Targeted Integration by Adeno-Associated Virus Matthew D. Weitzman, Samuel M. Young, Jr., Toni Cathomen, and Richard Jude Samulski
Development and Optimization of Adeno-Associated Virus Vector Transfer into the Central Nervous System Matthew J. During, Deborah Young, Kristin Baer, Patricia Lawlor, and Matthias Klugmann
A Method for Helper Virus-Free Production of Adeno-Associated Virus Vectors Roy F. Collaco and James P. Trempe
Novel Tools for Production and Purification of Recombinant Adeno-Associated Viral Vectors Julian D. Harris, Stuart G. Beattie, and J. George
... mehr
Dickson
Recombinant Adeno-Associated Viral Vector Types 4 and 5: Preparation and Application for CNS Gene Transfer Beverly L. Davidson and John A. Chiorini
Trans-Splicing Vectors Expand the Packaging Limits of Adeno-Associated Virus for Gene Therapy Applications Dongsheng Duan, Yongping Yue, Ziying Yan, and John F. Engelhardt
Generation of Retroviral Packaging and Producer Cell Lines for Large-Scale Vector Production with Improved Safety and Titer Thomas W. Dubensky, Jr. and Sybille L. Sauter
An Ecdysone-Inducible Expression System for Use with Retroviruses Karen Morse and John Olsen
In Vivo Infection of Mice by Replication-Competent MLV-Based Retroviral Vectors Estanislao Bachrach, Mogens Duch, Mireia Pelegrin, Hanna Dreja, Finn Skou Pedersen, and Marc Piechaczyk
Development of Simian Retroviral Vectors for Gene Delivery Biao Li and Curtis A. Machida
Self-Inactivating Lentiviral Vectors and a Sensitive Cre-loxP Reporter System Lung-Ji Chang and Anne-Kathrin Zaiss
Lentiviral Vectors for Gene Transfer to the Central Nervous System: Applications in Lysosomal Storage Disease Animal Models Deborah J. Watson and John H. Wolfe
A Highly Efficient Gene Delivery System Derived from Feline Immunodeficiency Virus (FIV) Sybille L. Sauter, Medhi Gasmi, and Thomas W. Dubensky, Jr
A Multigene Lentiviral Vector System Based on Differential Splicing Yonghong Zhu and Vicente Planelles
Production of Trans-Lentiviral Vector with Predictable Safety John C. Kappes, Xiaoyun Wu, and John K. Wakefield
Human Immunodeficiency Virus Type 1-Based Vectors for Gene Delivery to Human Hematopoietic Stem Cells Ali Ramezani and Robert G. Hawley Semliki Forest
Viral Vectors for Gene Transfer Jarmo Wahlfors and Richard A. Morgan Semliki
Forest Virus (SFV) Vectors in Neurobiology and Gene Therapy Kenneth Lundstrom and Markus U. Ehrengruber
Semliki Forest Virus Vectors for Large-Scale Production of Recombinant Proteins Kenneth Lundstrom
Development of Foamy Virus Vectors, George Vassilopoulos Neil C. Josephson, and Grant Trobridge
Poxviral/Retroviral Chimeric Vectors Allow Cytoplasmic Production of Transducing Defective Retroviral Particles Georg W. Holzer and Falko G. Falkner
Index
Recombinant Adeno-Associated Viral Vector Types 4 and 5: Preparation and Application for CNS Gene Transfer Beverly L. Davidson and John A. Chiorini
Trans-Splicing Vectors Expand the Packaging Limits of Adeno-Associated Virus for Gene Therapy Applications Dongsheng Duan, Yongping Yue, Ziying Yan, and John F. Engelhardt
Generation of Retroviral Packaging and Producer Cell Lines for Large-Scale Vector Production with Improved Safety and Titer Thomas W. Dubensky, Jr. and Sybille L. Sauter
An Ecdysone-Inducible Expression System for Use with Retroviruses Karen Morse and John Olsen
In Vivo Infection of Mice by Replication-Competent MLV-Based Retroviral Vectors Estanislao Bachrach, Mogens Duch, Mireia Pelegrin, Hanna Dreja, Finn Skou Pedersen, and Marc Piechaczyk
Development of Simian Retroviral Vectors for Gene Delivery Biao Li and Curtis A. Machida
Self-Inactivating Lentiviral Vectors and a Sensitive Cre-loxP Reporter System Lung-Ji Chang and Anne-Kathrin Zaiss
Lentiviral Vectors for Gene Transfer to the Central Nervous System: Applications in Lysosomal Storage Disease Animal Models Deborah J. Watson and John H. Wolfe
A Highly Efficient Gene Delivery System Derived from Feline Immunodeficiency Virus (FIV) Sybille L. Sauter, Medhi Gasmi, and Thomas W. Dubensky, Jr
A Multigene Lentiviral Vector System Based on Differential Splicing Yonghong Zhu and Vicente Planelles
Production of Trans-Lentiviral Vector with Predictable Safety John C. Kappes, Xiaoyun Wu, and John K. Wakefield
Human Immunodeficiency Virus Type 1-Based Vectors for Gene Delivery to Human Hematopoietic Stem Cells Ali Ramezani and Robert G. Hawley Semliki Forest
Viral Vectors for Gene Transfer Jarmo Wahlfors and Richard A. Morgan Semliki
Forest Virus (SFV) Vectors in Neurobiology and Gene Therapy Kenneth Lundstrom and Markus U. Ehrengruber
Semliki Forest Virus Vectors for Large-Scale Production of Recombinant Proteins Kenneth Lundstrom
Development of Foamy Virus Vectors, George Vassilopoulos Neil C. Josephson, and Grant Trobridge
Poxviral/Retroviral Chimeric Vectors Allow Cytoplasmic Production of Transducing Defective Retroviral Particles Georg W. Holzer and Falko G. Falkner
Index
... weniger
Bibliographische Angaben
- 2002, 592 Seiten, Maße: 23,5 cm, Gebunden, Englisch
- Herausgegeben von Machida, Curtis A.
- Verlag: Humana Press
- ISBN-10: 1588290190
- ISBN-13: 9781588290199
Sprache:
Englisch
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