Cancer Epigenetics / Epigenetics and Human Health Bd.11 (PDF)
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Epigenetic alterations are heritable changes that play a key role in human development and tissue-specific gene expression patterns. These changes can lead to alterations involved in tumor formation, imprinting, and metabolic disorders. Recent advances can help us understand the importance of epigenetic changes in both cancer development and tumor progression. In addition, epigenetic alterations may also be useful diagnostic and prognostic markers for the analysis of tumor progression.
Split into two parts, the book opens with a comprehensive overview of the identification and analysis of epigenetic changes in cancer and the consequences of such changes during tumor development. The second part focusses on cancer specific epigenetic alterations and discusses the potential use of epigenetic markers as biomarkers in diagnosis, early cancer progression, and prognosis. Moreover, it reviews the therapeutic potential of epigenetic drugs.
Given its scope, Cancer Epigenetics is an indispensable resource not only for researchers working in the field of human epigenetics and cancer research but also for advanced students seeking for an introduction into epigenetic mechanisms.
Professor Kalkan is a member of Turkish Medical Genetics Association (since 2006) and a member of the board of directors of the Turkish Cypriot Association of Human Genetics (since 2022).
During her PhD, her research focused on genetic and epigenetic alterations in brain tumors, especially in glioblastoma. She has published numerous articles in peer-reviewed journals and authored several chapters for various national and international books. Furthermore, she was involved in many research projects as project coordinator and assistant investigator. Her current research is focused on the identification of epigenetic and genetic alterations in cancer, obesity and post-menopausal term.
- 2023, 1st ed. 2023, 378 Seiten, Englisch
- Herausgegeben: Rasime Kalkan
- Verlag: Springer International Publishing
- ISBN-10: 3031423658
- ISBN-13: 9783031423659
- Erscheinungsdatum: 30.11.2023
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