Cardiovascular Effects of Inhaled Ultrafine and Nano-Sized Particles (ePub)

FOREWORD. PREFACE. THE EDITORS. CONTRIBUTORS. PART I. ISSUE FRAMING. CHAPTER 1 OVERVIEW (Flemming R. Cassee and Morton Lippmann). CHAPTER 2 ACUTE EFFECTS OF PARTICULATE MATTER ON THE RISK OF MYOCARDIAL INFARCTION (Krishnan Bhaskaran, Shakoor Hajat, and Liam Smeeth). CHAPTER 3 CHRONIC EFFECTS OF AIR POLLUTION ON CARDIOVASCULAR HEALTH (Ranjini M. Krishnan, Joel Kaufman, and Gerard Hoek). PART II. EXPOSURE. CHAPTER 4 PARTICLE CHARACTERIZATION (Thomas A.J. Kuhlbusch and Christof Asbach). CHAPTER 5 EXPOSURE ASSESSMENT FOR AMBIENT ULTRAFINE PARTICLES (Timo Lanki, Josef Cyrys, H.-Erich Wichmann, and Jeroen de Hartog). CHAPTER 6 FROM EXPOSURE TO DOSE (Werner Hofmann and Bahman Asgharian). CHAPTER 7 TRANSLOCATION OF INHALED NANOPARTICLES (Wolfgang G. Kreyling, Winfried Möller, Otmar Schmid, Manuela Semmler-Behnke, and Günter Oberdörster). CHAPTER 8 ROLE OF CHEMICAL COMPOSITION IN DETERMINING THE CARDIOVASCULAR EFFECTS OF PARTICLES (Andrew J. Ghio and Yuh-Chin T. Huang). PART III. METHODOLOGY. CHAPTER 9 IN VITRO STUDIES (Per E. Schwarze and Gerrit M. Alink). CHAPTER 10 EXPERIMENTAL STUDIES IN ANIMALS (Urmila P. Kodavanti, Lung-Chi Chen, and Daniel L. Costa). CHAPTER 11 HUMAN EXPOSURE STUDIES (Jeremy P. Langrish, Mark W. Frampton, and Anders Blomberg). CHAPTER 12 PANEL STUDIES (Joel Schwartz). PART IV. PARTICLES AND CARDIOVASCULAR DISEASE: MECHANISMS. A. ATHEROGENESIS. CHAPTER 13 PARTICULATES AND OXIDATIVE STRESS (Steffen Loft, Roel P.F. Schins, and Peter Møller). CHAPTER 14 ROLE OF INFLAMMATION IN THE ATHEROGENIC EFFECTS OF PARTICULATE MATTER (Thomas Sandström and David Newby). CHAPTER 15 INHALED PARTICLES, POSTPRANDIAL LIPIDS, AND THEIR POSSIBLE CONTRIBUTION TO ATHEROGENESIS: THE TROJAN HORSE HYPOTHESIS (Carlijne Hassing, Maarten J.M. Cramer, and Marcel Th.B. Twickler). CHAPTER 16 INHALED PARTICULATE MATTER AND ATHEROSCLEROSIS IN HUMANS (Barbara Hoffmann and Nino Künzli). CHAPTER 17 EFFECTS OF NANOPARTICLES ON THE PULMONARY VASCULATURE (Laurel E. Plummer, Kent E. Pinkerton,

Flemming R. Cassee is head of the Department of Inhalation
Toxicology, deputy head of the Center for Environmental Health, and
leader of the program on air pollution and health at the National
Institute for Public Health and the Environment (RIVM), Bilthoven,
the Netherlands.

Nicholas L. Mills is a British Heart Foundation Clinical Fellow
at the University of Edinburgh and Specialist Registrar in
Cardiology at the Royal Infirmary of Edinburgh.

David E. Newby is the British Heart Foundation John Wheatley
Chair of Cardiology at the University of Edinburgh. He is a
Consultant Interventional Cardiologist at the Royal Infirmary of
Edinburgh, Director of the Wellcome Trust Clinical Research
Facility, Director of the Clinical Research Imaging Centre, and
Director of Research and Development for NHS Lothian.

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