Molecular Motors (PDF)

BASIC PRINCIPLES OF MOTOR DESIGN Myosin Superfamily: An Overview (Kieke, Titus) Dynein Motors: Structure, Mechanochemistry and Regulation (King) Kinesin Superfamily Proteins (Hirokawa, Takemura) The Bacterial Flagellar Motor (Berry) F1-Motor of ATP Synthase (Noji) RNA and DNA Polymerases (Korzheva, Mustaev) Helicases as Molecular Motors (Levin, Patel) MECHANOCHEMISTRY How Protein Motors Convert Chemical Energy into Mechanical Work (Oster, Wang) Example Models to Illustrate the Difference between Ratchets and Power Strokes A Closer Look at Binding Free Energy Molecular Motor Directionality (Endow) Kinesins: Processivity and Chemomechanical Coupling (Hancock, Howard) Qantitative Measurements of Myosin Movement In Vitro: The Reductionist Approach Carried to Single Molecules (Spudich) Structure of Kinesin Motor Domains: Implications for Conformational Switching Involved in Mechanochemical Coupling (Song, Marx, Mandelkow) Single Molecule Measurements and Molecular Motors (Ishii, Yanagida) FUNCTIONAL IMPLICATIONS Mitotic Spindle Motors (Scholey, Mogilner) The Roles of Molecular Motors in Generating Developmental Asymmetry (Fischer) Motors and Membrane Trafficking (Verhey) Regulation of Molecular Motors (Haimo) Molecular Motors in Plant Cells (Reddy) MOTORS IN DISEASE Myosin Myopathies (Konhilas, Leinwand) The Role of Dynein in Disease (Vallee, Tai) Molecular Motors in Sensory Defects (Avraham) BEYOND BIOLOGICAL APPLICATIONS Systematized Engineering of Biomotor-powered Hybrid Devices (Schmidt, Montemagno) Synthetic Molecular Motors (Delden, Wiel, Koumura, Feringa)

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