Molecular Pathology in Drug Discovery and Development (PDF)

Covers powerful new tools for drug development

Molecular pathology offers tools and techniques that can greatly
enhance the drug discovery and development process, helping to make
the promises of personalized medicine a reality. Molecular
Pathology in Drug Discovery and Development provides an unmatched
guide to this cutting-edge discipline and its applications to
pharmaceutical science.

With contributions from leading lights in drug discovery, drug
development, and molecular pathology balanced by a consistent
editorial approach, this reference offers both an overview of
molecular pathology and a close look at the methods as they are
applied to the process of drug discovery and development. Presented
as steps in the drug development process, the coverage includes the
use of molecular pathology to:

* Identify and validate new drug candidates

* Enhance transcriptional profiling to better find and validate
biomarkers

* Assess toxicology

* Employ toxicogenomics to identify genes relevant to the safety
of compounds

* Identify correct doses for different drugs

* Identify patients for treatment

* Develop molecular therapies

* Further the new techniques of Immunohistochemistry and
Immunofluorescence

With many tests and treatments already working today, drug
research and development using molecular pathology has shown itself
an extremely fruitful area. Molecular Pathology in Drug Discovery
and Development gives practitioners an up-to-date resource on this
highly active discipline and its role in furthering pharmaceutical
research.