Risk Assessment for Chemicals in Drinking Water (PDF)

Contributors. Foreword. Preface. 1 Introduction to Drinking Water Risk Assessment (Robert A. Howd). Development of Drinking Water Regulations. The Risk Assessment Process. Public Perceptions and the Precautionary Principle. 2 Summary of the Development of Federal Drinking Water Regulations and Health-Based Guidelines for Chemical Contaminants (Joyce Morrissey Donohue and Wynne Maynor Miller). Selecting Candidates for Regulatory Consideration. Key Components for Regulatory Development. Development of Regulatory Values. Nonregulatory Options. 3 Interpretation of Toxicologic Data for Drinking Water Risk Assessment (Robert A. Howd and Anna M. Fan). Animal Toxicity Studies. Human Toxicity Studies. Conclusions. 4 Exposure Source and Multiroute Exposure Considerations for Risk Assessment of Drinking Water Contaminants(Kannan Krishnan and Richard Carrier). Exposure Source Considerations in Risk Assessment. Routes of Exposure and Dose Calculations. 5 Toxicokinetics for Drinking Water Risk Assessment (John C. Lipscomb). Evaluation of Toxicity Data. Toxicokinetics: PBPK Modeling. Risk Assessment. Conclusions. 6 Health Risk Assessment of Chemical Mixtures in Drinking Water (Richard C. Hertzberg, Glenn E. Rice, Linda K. Teuschler, J. Michael Wright, and Jane E. Simmons). Drinking Water Mixture Concerns. Estimating Exposures to Multiple Chemicals in Drinking Water. Toxicological Concepts for Joint Toxicity. Chemical Mixtures Risk Assessment Methods. New Approaches for Assessing Risk from Exposure to Drinking Water Mixtures. Conclusions. References. 7 Protection of Infants, Children, and Other Sensitive Subpopulations (George V. Alexeeff and Melanie A. Marty). Factors Influencing Differences in Susceptibility Between Infants and Children and Adults. Critical Systems and Periods in Development. Age at Exposure and Susceptibility to Carcinogens. Drinking Water Standards Developed to Protect Sensitive. Subpopulations. References. 8 Risk Assessment for Essential Nutrients (Joyce

ROBERT A. HOWD is Chief of the Water Toxicology Section in the Office of Environmental Health Hazard Assessment of the California EPA, supervising the production of California Public Health Goals for chemicals in drinking water. Dr. Howd has authored or coauthored over fifty formal scientific publications and numerous government reports.

ANNA M. FAN is Chief of the Pesticide and Environmental Toxicology Branch, Office of Environmental Health Hazard Assessment, California EPA. Dr. Fan has served on the U.S. EPA Science Advisory Board, Drinking Water Committee; the U.S. EPA Endocrine Disruptors Screening and Testing Advisory Committee; and other national advisory committees. She is an editor of the Journal of Environmental Science and Health, Part C: Environmental Carcinogenesis and Ecotoxicology Reviews.

Dieses eBook können Sie uneingeschränkt auf allen Geräten der tolino Familie lesen. Zum Lesen auf sonstigen eReadern und am PC benötigen Sie eine Adobe ID.