Studies on Arthritis and Joint Disorders / Oxidative Stress in Applied Basic Research and Clinical Practice (PDF)
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Joint diseases are a major public health concern. Reactive oxygen species are mediators in pathways associated with joint tissue injury. Oxidative Stress in Applied Basic Research and Clinical Practice: Studies on Arthritis and Joint Disorders provides background to understanding the role of reactive oxygen species in joint diseases, as well as therapeutic strategies for their regulation. International experts discuss recent advances on experimental and clinical data focused on free radical-mediated mechanisms of disease. The book also addresses the protective role of antioxidants against the insult of reactive oxygen species in rheumatic diseases.
Dr. Oreste Gualillo obtained his PhD in Pharmacology at the Department of Experimental Pharmacology of the University "Federico II", Naples (Italy). He received training in molecular endocrinology under Prof. Paul A. Kelly at the Necker School of Medicine, Paris. In 1998 he moved to the Laboratory of Molecular Endocrinology of the University of Santiago de Compostela, Spain, where he worked as a Marie Curie postdoctoral research fellow. In 2001 he set up his own research group at the Santiago University Clinical Hospital. He is currently a Class "A" Stable researcher with the SERGAS (Servizo Galegode Saude) and Carlos III Health Institute of the Spanish Ministry of Health, heading the NEIRID (NeuroEndocrine
Olga Sánchez-Pernaute, MD, PhD, is a senior rheumatologist in the Jimenez Diaz Foundation University Hospital and assistant Prof at the Autonoma University School of Medicine in Madrid. She has a dilated background in translational research, focused on the study of innate mechanisms of disease associated to autoimmune rheumatic conditions. Of note are her early contributions to the field of inflammatory mediators in experimental models of arthritis, and the pioneer work on the role of fibrin in the progression of synovitis. She was invited for a one-year fellowship at the Laboratory of Experimental Rheumatology of Zürich University, where she developed her research interest in epigenetics. In the last few years she has created a Multidisciplinary Unit for Systemic Autoimmune Diseases that she currently directs at her Institution.
- 2013, 2013, 411 Seiten, Englisch
- Herausgegeben: Maria Jose Alcaraz, Oreste Gualillo, Olga Sánchez-Pernaute
- Verlag: Springer-Verlag GmbH
- ISBN-10: 1461461669
- ISBN-13: 9781461461661
- Erscheinungsdatum: 20.02.2013
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