Vaccines development and manufacturing process (PDF)

Essay from the year 2016 in the subject Health - Public Health, grade: 80/100, , course: Tropical Medicine-Immuniwation and surveillance, language: English, abstract: This paper explains how vaccines are developed and describes in detail their manufacturing process

The Greeks had two gods of health: Aesculapius and Hygieia, therapy and prevention, respectively. Medicine in the twentieth century retains those two concepts, and vaccination is a powerful means of prevention. Vaccines provide the immunity that comes from natural infection without the consequences of natural infection; help protect people from harmful infections before they come in contact with the disease. Vaccines may also help alleviate the symptoms of the infection caused by the virus.Vaccines provide the immunity that comes from natural infection without the consequences of natural infection.

Vaccine development is difficult, complex, highly risky, and costly and includes clinical development, process development and assay development. Vaccine development requires strong management systems and controls, and requisite skill sets among scientists and engineers. Pharmaceutical companies must demonstrate the safety and efficacy of a medicinal product or vaccine through the use of clinical trials, before a regulatory authority registers the product. The vast majority of over one billion doses of vaccines manufactured worldwide each year are given to perfectly healthy individuals. It is this fact that drives the requirements for vaccines to be among the most rigorously designed, monitored and compliant products manufactured today.