Sphingolipids in Cancer
Sphingolipids in Cancer, Volume 140, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Topics discussed in this updated volume include Mechanisms of...
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Sphingolipids in Cancer, Volume 140, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Topics discussed in this updated volume include Mechanisms of ceramide-dependent cancer cell death, Sphingolipids as regulators of autophagy and endocytic trafficking, The role and function of sphingomyelin biosynthesis in the development of cancer, Neutral sphingomyelinases in cancer: Friend or foe?, Sphingolipid rendezvous at the crossroad of NAFLD and senescence, Ceramide signaling and p53 pathways, Sphingolipid regulation of RNA Biology in cancer phenotypes, The role of ceramide-1-phosphate in tumor cell survival and dissemination, and more.
Bibliographische Angaben
- Herausgegeben:Chalfant, Charles E.; Fisher, Paul B.
- Verlag: Academic Press
- EAN: 9780128142233
Autoren-Porträt
Professor Charles E. Chalfant heads up the Chalfant Laboratory and is the director of the Lipidomic Facility at Virgina Commonwealth University. The Chalfant laboratory is currently focused on two major areas of cell signaling and human pathophysiologies: 1) lipid and oncogenic regulation of alternative splicing; and 2) the regulation of eicosanoid synthesis in inflammation and cancer.
Inhaltsverzeichnis zu „Sphingolipids in Cancer “
1. Mechanisms of ceramide-dependent cancer cell death Rose Nganga, Natalia Oleinik and Besim Ogretmen 2. Sphingolipids as regulators of autophagy and endocytic trafficking Megan M. Young and Hong-Gang Wang 3. Role and function of sphingomyelin biosynthesis in the development of cancer Giovanni D'Angelo, Sitapriya Moorthi and Chiara Luberto 4. Neutral sphingomyelinases in cancer: friend or foe? Christopher J. Clarke 5. Ceramide and exosomes: a novel target in cancer biology and therapy Ahmed Elsherbini and Erhard Bieberich 6. Sphingolipids at the crossroads of NAFLD and senescence Mariana Nikolova-Karakashian 7. Ceramide signaling and p53 pathways Kristen Jeffries and Natalia Krupenko 8. The role of ceramide 1-phosphate in tumor cell survival and dissemination Antonio Gomez-Muñoz 9. The onus of sphingolipid enzymes in cancer drug resistance Samy A.F. Morad and Myles C. Cabot 10. Interdiction of sphingolipid metabolism revisited: focus on prostate cancer Christina Voelkel-Johnson, James S. Norris and Shai White-Gilbertson 11. Targeting sphingosine kinases for the treatment of cancer Clayton S. Lewis, Christina Voelkel-Johnson and Charles D. Smith 12. Novel sphingolipid-based cancer therapeutics in the personalized medicine era Jeremy Shaw, Pedro Costa-Pinheiro, Logan Patterson, Kelly Drews, Sarah Spiegel and Mark Kester 13. Side effects in cancer therapy: are sphingolipids to blame? Falak Patel and Stefka D. Spassieva
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