Cancer Proteomics

PART 1 PROTEOMICS TECHNOLOGIES Current and emerging mass spectrometry instrumentation and methods for proteomic analyses. Belinda Willard, Suma Kaveti and Michael T. Kinter PART 2 CELL SIGNALING PROTEOMICS 2 Integration of genomics and proteomics in dissecting p53 signaling. Kyunghee Lee, Tao Wang, Abdur Rehman, Yuhua Wang, Sayed S. Daoud 3 Proteomic profiling of tyrosine kinases as pharmacological endpoints for targeted cancer therapy. Moulay A. Alaoui-Jamali and Devanand Pinto PART 3 TUMOR PROTEOMICS Oncoproteomics for personalized management of cancer. K. K. Jain Application of serum and tissue proteomics to understand and detect solid tumors. Christina M. Annunziata, Dana M. Roque, Nilofer Azad, Elise C. Kohn Insight on renal cell carcinoma proteome. Cecilia Sarto, Vanessa Proserpio, Fulvio Magni, Paolo Mocarelli Proteomics in lung cancer. M.A. Reymond, M. Beshay, H. Lippert Proteomic strategies of therapeutic individualization and target discovery in acute myeloid leukemia. Bjørn Tore Gjertsen, Gry Sjøholt New tumor biomarkers: Practical considerations prior to clinical application. Nils Brünner, Mads Holten-Andersen, Fred Sweep, John Foekens, Manfred Schmitt, Michael J Duffy PART 4 BIOINFORMACTICS AND REGULATORY ASPECTS OF PROTEOMICS Annotating the human proteome: From establishing a parts list to a tool for target identification. Rolf Apweiler and Michael Mueller Regulatory aspects of the oncology drug-diagnostics co-development process by proteomics approach. Dave Li, Joseph Hackett, Maria Chan, GenePennello, Steve Gutman

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