Symposium in Immunology III

Basic Biology.- Introductory Remarks.- B Cell Development in the Mouse: Scenarios for Defects Expressed in the B Cell Lineage.- Factors and Receptors Involved in the Selection of B Lymphocytes Responding to T-Dependent Antigen.- Antibody Activities of Human Monoclonal Immunoglobulins.- Immune Regulation, Biology, Pathology.- Human Types 1 and 2 T Helper Subsets: Functional Properties, Role in Disease and Regulation of Development.- The Use of Targeted Mutations in ES Cells to Create Novel Immunodeficient Mouse Models.- BTK, A Novel Protein Tyrosine Kinase Mutated in X-Linked Agammaglobulinemia.- Clinics.- Clinical and Immunological Aspects of Common Variable Immunodeficiency.- Clinical Relevance of Subclass Deficiency Diseases.- Different Categories of Common Variable Immunodeficiency.- Immunoregulatory Effects of Immunoglobulin D.- Mucosal Immunity in Immunodeficiency.- Strategies in the Diagnosis and Treatment of Immunodeficiency Diseases.- Therapy.- Immunodeficiency with Normal or Increased Immunoglobulin M.- Modulation of the Inflammatory Response by Human Immunoglobulin A.- Intravenous Immunoglobulins in the Treatment of Recurrent Seizures.- Role of Cytokines in the Regulation of Malignant B Cell Proliferation.