Adipose Tissue and Cancer
(Sprache: Englisch)
This book discusses data suggesting the role of adipose tissue in cancer, and examines mechanisms - such as tumor vascularization and immune system suppression - through which excess or restriction of adipose tissue could influence cancer progression.
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This book discusses data suggesting the role of adipose tissue in cancer, and examines mechanisms - such as tumor vascularization and immune system suppression - through which excess or restriction of adipose tissue could influence cancer progression.
Klappentext zu „Adipose Tissue and Cancer “
Recent studies have shown that cells from adipose tissue are capable of trafficking to tumors, thus enabling paracrine action of adipokines from within the tumor microenvironment. Increased tumor vascularization, immune system suppression and direct effects on malignant cell survival and proliferation have been investigated as mechanisms regulated by adipokines. The goal of this book is to discuss data pointing to the role of adipose tissue in cancer and to dissect individual mechanisms through which adipose tissue excess or restriction could influence cancer progression.
Inhaltsverzeichnis zu „Adipose Tissue and Cancer “
Preface: Obesity, Adipose Tissue and Cancer Progression.- Metabolic Perturbations Associated with Adipose Tissue Dysfunction and the Obesity-Cancer Link.- Increased Adiposity and Colorectal Cancer.- Adiposity and Diabetes in Breast and Prostate Cancer.- Increased Adipocity and Endometrial Cancer Risk.- Adipokines: Soluble Factors from Adipose Tissue Implicated in Cancer.- Animal Models to Study the Interplay between Cancer and Obesity.- Unraveling the local influence of tumor-surrounding adipose tissue on tumor progression: cellular and molecular actors involved.- Trafficking of Cells from Adipose Tissue to Tumor Microenvironment.- The Impact of Obesity Intervention on Cancer: Clinical Perspectives.- Index.
Bibliographische Angaben
- 2015, Softcover reprint of the original 1st ed. 2013, VIII, 190 Seiten, Maße: 15,5 x 23,5 cm, Kartoniert (TB), Englisch
- Herausgegeben: Mikhail G. Kolonin
- Verlag: Springer, Berlin
- ISBN-10: 1489989196
- ISBN-13: 9781489989192
Sprache:
Englisch
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