Advances in Dementia Research

White matter changes: the clinical consequences in the aging population.- Longitudinal change of white matter abnormalities.- Genetic aspects of microangiopathy-related cerebral damage.- Research criteria for subcortical vascular dementia in clinical trials.- How can cerebral infarcts and hemorrhages lead todementia?.- Vascular aspects in Alzheimer's disease.- Novel imaging technologies in the assessment of cerebral ageing and vascular dementia.- Alzheimer disease and neuroinflammation.- The immunological microenvironment in the CNS: implications on neuronal cell death and survival.- Toxic effector molecules in the pathogenesis of immune-mediated disorders of the central nervous system.- Cytokines in CNS disorders: neurotoxicity versus neuroprotection.- Do neuronal inclusions kill the cell?.- Mechanisms of cell death in neurodegenerative disorders.- Estrogens, apoptosis and cells of neural origin.- Markers of apoptosis and models of programmed cell death in Alzheimer's disease.- Mitochondrial dysfunction and oxidative stress in aging and neurodegenerative disease.- Genetics of Alzheimer's disease - routes to the pathophysiology.- Secretion of the amyloid precursor protein is elevated isoform specifically by apolipoprotein E4.- Alterations in neurotrophins and neurotrophin receptors in Alzheimer's disease.- Genetically altered transgenic models of Alzheimer's disease.- Morphological substrates of mental dysfunction in Lewy body disease: an update.- Mechanism of neurofibrillary degeneration and pharmacologic therapeutic approach.- Understanding the role of estrogen on cognition and dementia.- Present and future of Alzheimer therapy.- Trials to slow progression and prevent disease onset.- Epidemiologic clues to the causes and routes to prevention of Alzheimerdisease.- Post-transcription modulation of the blood-brain barrier GLUT1 glucose transporter by brain-derived factors.- A brain derived peptide preparation reduces the translation dependent loss of a cytoskeletal