Advances in Research on Neurodegeneration

Huntington disease: insights on the role of huntingtin cleavage.- PARKIN as a pathogenic gene for autosomal recessive juvenile parkinsonism.- Autosomal-dominantly inherited forms of Parkinson's disease.- Role of anti-apoptotic Bcl-2 protein in spinal muscular atrophy.- Subcellular localization of ?-synuclein in primary neuronal cultures: effect of missense mutations.- Roles of A? and carboxyl terminal peptide fragments of amyloid precursor protein in Alzheimer disease.- Iron chelating, antioxidant and cytoprotective properties of dopamine receptor agonist; apomorphine.- The motor circuit of the human basal ganglia reconsidered.- Involvement of endogenous N-methyl(R)salsolinol in Parkinson's disease: induction of apoptosis and protection by (-)deprenyl.- The myelin oligodendrocyte glycoprotein (MOG): a model for antibody-mediated demyelination in experimental autoimmune encephalomyelitis and multiple sclerosis.- Role of caspase-1 sub-family in cytotoxic cytokine-induced oligodendrocyte cell death.- Cytokines in Parkinson's disease.- Apoptosis as a general cell death pathway in neurodegenerative diseases.- Dentatorubral-pallidoluysian atrophy (DRPLA).- Gene therapy of Parkinson's disease using Adeno-Associated Virus (AAV) vectors.- Mechanisms of tissue injury in multiple sclerosis: opportunities for neuroprotective therapy.- Optic-spinal form of multiple sclerosis and immune-mediated myelopathy in Japan.