Aging and Heart Failure
Mechanisms and Management
(Sprache: Englisch)
This book synthesizes the major research advances in molecular, biochemical and translational aspects of aging and heart failure over the last four decades and addresses future directions in management and drug discovery. It presents clinical issues and...
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Klappentext zu „Aging and Heart Failure “
This book synthesizes the major research advances in molecular, biochemical and translational aspects of aging and heart failure over the last four decades and addresses future directions in management and drug discovery. It presents clinical issues and molecular mechanisms related to heart failure, including the changing demographics in the aging population with heart failure; hypertension and prevention of diastolic heart failure in the aging population; polypharmacy and adverse drug reactions in the aging population with heart failure; changes in the heart that accompany advancing age from humans to molecules; aging-associated alterations in myocardial inflammation and fibrosis and aging-related changes in mitochondrial function and implications for heart failure therapy. The book succinctly summarizes the large volume of data on these key topics and highlights novel pathways that need to be explored. Featuring contributions from leading clinician-scientists, Aging and Heart Failure: Mechanisms and Management is an authoritative resource on the major clinical issues in heart failure therapy in the elderly for cardiologists, gerontologists and internists.
Inhaltsverzeichnis zu „Aging and Heart Failure “
Ch. 1: Changing demographics of the aging population with heart failure and implications for therapyBodh I. Jugdutt
Ch. 2: Biology of aging and implications for heart failure therapy and prevention
Bodh I. Jugdutt
Ch. 3: Hypertension and prevention of diastolic heart failure in the aging population
Wilbert S. Aronow
Maciej Banach
Ali Ahmed
Ch. 4: Aging and optimal therapy of systolic heart failure in the elderly
Nakul Chander Sharma
Bodh I. Jugdutt
Ch. 5: Atrial fibrillation and heart failure in the aging population
Pedram Kazemian
Bodh I. Jugdutt
Ch. 6: Optimizing therapy of heart failure in the aging population with monitoring in clinics
John R. Dimitry
Justin A. Ezekowitz
Ch. 7: Cardiac alterations in aging, hypertension and diastolic heart failure
Edith Pituskin
D. Ian Paterson
Ch. 8: Polypharmacy and adverse drug reactions in the aging population with heart failure
Michael W. Rich
William J. Nienaber
Ch. 9: Aging-related changes in vascular biology and implications for heart failure therapy in the aging population
Michael Sean McMurtry
Ch. 10: Biomarkers and optimal management of heart failure in the aging population
Hanna K. Gaggin
James L. Januzzi, Jr.
Ch. 11: Benefits of Exercise in the elderly
Ezra A. Amsterdam
C. Tissa Kappagoda
Ch. 12: The RAAS in heart failure: an update on clinical trials and opportunities for therapy
C. Tissa Kappagoda
Ezra A. Amsterdam
Ch. 13: Aging and diastolic dysfunction - the interplay of inflammation and extracellular matrix regulation
Peter Moritz Becher
Dirk Westermann,
Carsten Tschöpe
Ch. 14: Reperfusion and vasodilator therapy in elderly patients with STEMI and
... mehr
heart failure. Improving outcomes
Bodh I. Jugdutt,
Anwar Jelani
Seraj Abualnaja
Nakul Chander Sharma
Joseph Szeman Wong
Ch. 15: Erythropoietin therapy for heart failure
Margarita Borovka
Mathew S. Maurer
Ch. 16: Role of resistin in heart failure in the elderly
Yasuchika Takeishi
Ch. 17: Role of coronary artery calcium in cardiovascular risk stratification and management in the aging population
Craig R. Butler
Paolo Raggi
Ch. 18: Aging-and remodeling of the RAS and RAAS and related pathways. Implications for heart failure therapy
Bodh I. Jugdutt
Ch. 19: Aging and right ventricular failure from pulmonary hypertension: Effect of right ventricular and pulmonary artery remodeling
Joseph Szeman Wong
Bodh I. Jugdutt
Ch. 20: Biomarkers of cardiovascular aging
Nirankar S. Neki
Paramjit S. Tappia
Naranjan S. Dhalla
Ch. 21: Changes in the heart that accompany advancing age: Humans to molecules
Edward G. Lakatta
Harold A. Spurgeon
Andzej M. Janczewski
Ch. 22: Aging-related changes in cell death and cell survival pathways and implications for heart failure therapy
Guido R.Y. De Meyer
Dorien M. Schrijvers
Wim Martinet
Ch. 23: Aging-related changes in telomeres and telomerases and implications for heart failure therapy
Pim van der Harst
Dirk J. van Veldhuisen
Ch. 24: Aging associated alterations in myocardial inflammation and fibrosis: pathophysiological perspectives and clinical implications
Arti V. Shinde
Nikolaos G Frangogiannis
Ch. 25: Aging-related changes in extracellular matrix: implications for ventricular remodeling following myocardial infarction
Nguyen T. Nguyen
Andriy Yabluchanskiy
Lisandra E. de Castro Brás
Yu-Fang Jin
Merry L. Lindsey
Ch. 26: Calcium handling defects and changes in cardiac function in the aging heart
Adriana Adameova
Nirankar S. Neki
Paramjit S. Tappia
Naranjan S. Dhalla
Ch. 27: Integrins: Implications for aging in heart failure therapy
Laura L. Daniel
William L. Joyner
Mahipal Singh
Krishna Singh
Ch. 28: Adipokines as novel biomarkers in aging and heart failure
Ken Shinmura
Ch. 29: Aging-related changes in cellular and molecular mechanisms of post-infarction remodeling. Implications for heart failure therapy
Henry Han-Jen Shih
Andrew J. Boyle
Ch. 30: Aging-related changes in mitochondrial function and implication for heart failure therapy
Satoaki Matoba
Atsushi Hoshino
Hiroaki Matsubara
Ch. 31: Regulation of SERCA via oxidative modifications: Implications for the pathophysiology of diastolic dysfunction in the aging heart
Fuzhong Qin
Richard A. Cohen
Wilson S. Colucci
Ch. 32: SMP-30 and aging-related cardiac remodeling and heart failure
Satoshi SuzukiYasuchika Takeishi
Bodh I. Jugdutt,
Anwar Jelani
Seraj Abualnaja
Nakul Chander Sharma
Joseph Szeman Wong
Ch. 15: Erythropoietin therapy for heart failure
Margarita Borovka
Mathew S. Maurer
Ch. 16: Role of resistin in heart failure in the elderly
Yasuchika Takeishi
Ch. 17: Role of coronary artery calcium in cardiovascular risk stratification and management in the aging population
Craig R. Butler
Paolo Raggi
Ch. 18: Aging-and remodeling of the RAS and RAAS and related pathways. Implications for heart failure therapy
Bodh I. Jugdutt
Ch. 19: Aging and right ventricular failure from pulmonary hypertension: Effect of right ventricular and pulmonary artery remodeling
Joseph Szeman Wong
Bodh I. Jugdutt
Ch. 20: Biomarkers of cardiovascular aging
Nirankar S. Neki
Paramjit S. Tappia
Naranjan S. Dhalla
Ch. 21: Changes in the heart that accompany advancing age: Humans to molecules
Edward G. Lakatta
Harold A. Spurgeon
Andzej M. Janczewski
Ch. 22: Aging-related changes in cell death and cell survival pathways and implications for heart failure therapy
Guido R.Y. De Meyer
Dorien M. Schrijvers
Wim Martinet
Ch. 23: Aging-related changes in telomeres and telomerases and implications for heart failure therapy
Pim van der Harst
Dirk J. van Veldhuisen
Ch. 24: Aging associated alterations in myocardial inflammation and fibrosis: pathophysiological perspectives and clinical implications
Arti V. Shinde
Nikolaos G Frangogiannis
Ch. 25: Aging-related changes in extracellular matrix: implications for ventricular remodeling following myocardial infarction
Nguyen T. Nguyen
Andriy Yabluchanskiy
Lisandra E. de Castro Brás
Yu-Fang Jin
Merry L. Lindsey
Ch. 26: Calcium handling defects and changes in cardiac function in the aging heart
Adriana Adameova
Nirankar S. Neki
Paramjit S. Tappia
Naranjan S. Dhalla
Ch. 27: Integrins: Implications for aging in heart failure therapy
Laura L. Daniel
William L. Joyner
Mahipal Singh
Krishna Singh
Ch. 28: Adipokines as novel biomarkers in aging and heart failure
Ken Shinmura
Ch. 29: Aging-related changes in cellular and molecular mechanisms of post-infarction remodeling. Implications for heart failure therapy
Henry Han-Jen Shih
Andrew J. Boyle
Ch. 30: Aging-related changes in mitochondrial function and implication for heart failure therapy
Satoaki Matoba
Atsushi Hoshino
Hiroaki Matsubara
Ch. 31: Regulation of SERCA via oxidative modifications: Implications for the pathophysiology of diastolic dysfunction in the aging heart
Fuzhong Qin
Richard A. Cohen
Wilson S. Colucci
Ch. 32: SMP-30 and aging-related cardiac remodeling and heart failure
Satoshi SuzukiYasuchika Takeishi
... weniger
Bibliographische Angaben
- 2016, Softcover reprint of the original 1st ed. 2014, XXII, 475 Seiten, 50 farbige Abbildungen, Maße: 17,8 x 25,6 cm, Kartoniert (TB), Englisch
- Herausgegeben: Bodh I. Jugdutt
- Verlag: Springer, Berlin
- ISBN-10: 1493944231
- ISBN-13: 9781493944231
Sprache:
Englisch
Pressezitat
From the reviews:"This book details the clinical, physiological, and molecular aspects of heart failure pathophysiology, diagnosis, and management. ... The book caters mainly to advanced care practitioners in adult cardiovascular disease and primary care, including physicians, physician assistants, and nurse practitioners. Investigators with an interest in the molecular changes of the aging cardiovascular system also would benefit from this book. Finally, nurses who are part of a heart failure team or care for patients with cardiovascular complications will find it useful." (Shawn Ragbir, Doody's Book Reviews, June, 2014)
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