An Efficient Pyrimidine Scaffolds against Bacterial Strains
Pyrimidine Derivatives
(Sprache: Englisch)
A series of novel 2-(substituted benzylidene)-7-(4-bromophenyl)-5-(furan-2-yl)-2H-thiazolo[3,2-a]pyrimidin-3(7H)-ones were synthesized by using established methods and were characterized by IR, 1H NMR and Mass spectroscopy in order to confirm their...
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A series of novel 2-(substituted benzylidene)-7-(4-bromophenyl)-5-(furan-2-yl)-2H-thiazolo[3,2-a]pyrimidin-3(7H)-ones were synthesized by using established methods and were characterized by IR, 1H NMR and Mass spectroscopy in order to confirm their formation. These compounds were synthesized to evaluate their antitubercular, antibacterial and antifungal potency. Docking studies revealed the importance of functional groups and its different biological action. They were found to be potent against Mycobacterium tuberculosis H37Ra strain, also potent against Gram +ve, Gram -ve and fungal strains
Bibliographische Angaben
- Autoren: Theivendren Panneer Selvam , Vijaysarathy D. Phadte , Silveira Karyn Valzita
- 2013, 168 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 3659428515
- ISBN-13: 9783659428517
Sprache:
Englisch
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