Angiogenesis in Health, Disease and Malignancy
(Sprache: Englisch)
This book is about "Angiogenesis". A process in which new vasculature is formed from pre-existing capillaries. Angiogenesis process is associated with the proliferation and growth of both physiologically normal and neoplastic tissues, through the...
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Klappentext zu „Angiogenesis in Health, Disease and Malignancy “
This book is about "Angiogenesis". A process in which new vasculature is formed from pre-existing capillaries. Angiogenesis process is associated with the proliferation and growth of both physiologically normal and neoplastic tissues, through the formation of vascular supply, essential for delivering growth requirements such as oxygen and nutrients.
The book describes more than 100 genes and their key regulatory functions in the context of normal healthy condition, disease and malignancy, cancer proliferation and progression. New insights into the role of angiogenesis and the therapeutic inhibition of its regulators are investigated, due to the great potential for exploitation in the development of a novel treatment for cancer.
New scientists, junior researchers and biomedical science students will find this book an invaluable introductory reference to their insight about angiogenesis and angiogenic role of more than 100 angiogenes and their role in healthy, disease and malignant conditions.
Inhaltsverzeichnis zu „Angiogenesis in Health, Disease and Malignancy “
1. Introduction to Angiogenesis in Normal Physiology. Disease and Malignancy
2. Adenosine triphosphate-binding cassette (ABC) lipid transporters
3. Angiogenin
4. Angiopoietins5. Angiotropin
6. C-KIT: tyrosine kinase receptors with potential to initiate
7. CCND1 and E1
8. Cluster of Differentiation 71 (CD71)
9. Connective Tissue Growth Factor (CTGF)
10. COX10
11. Cysteine-rich 61 (Cyr61)
12. Epidermal growth factor
13. Epidermal growth factor domain-like 7 (EGFL7)
14. Erythropoietin-producing hepatocellular receptors A: Ephrin A1, Ephrin A2 and Ephrin A3
15. Erythropoietin-producing hepatocellular receptors B: Ephrin B2, Ephrin B4
16. Ets-1
17. Fibrin
18. Fibroblast growth factors (Acidic: FGF-1; Basic: FGF-2) and its receptors (FGFR)
19. Fibronectin
20. Granulocyte-Macrophage and Granulocyte Colony Stimulating Factor (GM-CSF and G-CSF)
21. GAX and HOXA5
22. Heparanase
23. Hepatocyte Growth Factor (HGF)
24. HIF-1
25. Insulin-like growth factor
26. Integrins ( v1beta3, v1beta5, beta8)
27. Interleukins
28. Insulin receptor substrate (IRS1)
29. Iron-sulfur clusters (ISCU)
30. MDM4
31. Matrix Metalloproteinase 2 (MMP2)
32. Monobutyrin
33. Neutrophil activating protein-2 (NAP-2)
34. p27kip1 and p57Kip2 (CDKN1B and CDKN1C)
35. Platelet-derived endothelial cell growth factor (PDGF)
36. Prolyl hydroxylase domain-2 (PHD-2)
37. Phosphatidylinositol-4, 5-bisphosphate 3-kinase (PIK3Ca)
38. PIK3R2 (p85beta) - Phosphatidylinositol 3-kinase beta-subunit
39. Platelet-activating factor
40. Placenta growth factor (PlGF)
... mehr
41. Preproendothelin-1 (PreproET-1)
42. Proliferin
43. Prostaglandins
44. ROS1
45. SIRT1
46. SMAD4 (Mothers against Decapentaplegic Homolog 4)
47. Sprouty-Related, EVH1 Domain-containing protein 1 (SPRED-1)
48. Signal transducer and activator of transcription of 5A and S3 (STAT5 and STATS3)
49. SUFU
50. Tenascins51. Tissue inhibitor of metalloproteinases 1 and 2 (TIMP-1 and TIMP-2)
52. Tissue factor gene
53. Transforming growth factor and beta (TGF- and TGF- beta)
54. Transforming growth factor beta-receptor type II (TGFbetaR2)
55. TSP-1
56. Tumour necrosis factor- (TNF- )
57. Urokinase plasminogen activator
58. Vascular Endothelial Growth Factor (VEGF)
59. Vascular cell adhesion molecule-1 (VCAM-1)
60. Vascular endothelial (VE)-Cadherin
61. Zinc Finger E-Box Binding Homeobox 1 (ZEB1)
62. Miscellaneous genes involved in Angiogenesis in Normal Physiology, Disease and Malignancy
41. Preproendothelin-1 (PreproET-1)
42. Proliferin
43. Prostaglandins
44. ROS1
45. SIRT1
46. SMAD4 (Mothers against Decapentaplegic Homolog 4)
47. Sprouty-Related, EVH1 Domain-containing protein 1 (SPRED-1)
48. Signal transducer and activator of transcription of 5A and S3 (STAT5 and STATS3)
49. SUFU
50. Tenascins51. Tissue inhibitor of metalloproteinases 1 and 2 (TIMP-1 and TIMP-2)
52. Tissue factor gene
53. Transforming growth factor and beta (TGF- and TGF- beta)
54. Transforming growth factor beta-receptor type II (TGFbetaR2)
55. TSP-1
56. Tumour necrosis factor- (TNF- )
57. Urokinase plasminogen activator
58. Vascular Endothelial Growth Factor (VEGF)
59. Vascular cell adhesion molecule-1 (VCAM-1)
60. Vascular endothelial (VE)-Cadherin
61. Zinc Finger E-Box Binding Homeobox 1 (ZEB1)
62. Miscellaneous genes involved in Angiogenesis in Normal Physiology, Disease and Malignancy
... weniger
Bibliographische Angaben
- Autor: Ali Salajegheh
- 2018, Softcover reprint of the original 1st ed. 2016, 423 Seiten, Maße: 15,5 x 23,5 cm, Kartoniert (TB), Englisch
- Verlag: Springer, Berlin
- ISBN-10: 331980281X
- ISBN-13: 9783319802817
Sprache:
Englisch
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