Anti-oxidant and Computational Study of Select Aromatic compounds

The book entitled "Anti-oxidant Bioassay and Computational Study of Select Aromatic Compounds" is divided into seven chapters.Chapter-1 introduces the in vitro spectrophotometric antioxidant bioassay, its applications and methods. The bioassay is expressed in terms of IC50 values, QSAR and Molecular modeling studies. This is a detailed description of semi-empirical methods, evaluation of physicochemical parameters, energy minimization methods, regression analysis and docking studies. Chapter-2 deals with experimental details and molecular modeling methodologies. It consists of different experimental methods viz., freeradical scavenging activity, calculation of IC50 values, docking studies. Chapter-3 deals with novel anti-oxidant bioassay, QSAR and docking studies of 1-phenyl, 3-(nitro furan) prop-2-ene-1-one derivatives. In Chapter-4, design of beta-aminoketone analogues as antioxidants has been dealt in terms of bioassay and computational studies. Towards the end of the book Chapter-5, 6 &7 consists of novel in vitro antioxidant bioassay, QSAR and docking studies of thienopyridine , triazole and Oxo-quinoline derivatives.