Antimicrobial Chemotherapy

Historical Introduction; PART I: GENERAL PROPERTIES OF ANTIMICROBIAL AGENTS; 1. Inhibitors of bacterial cell wall synthesis; 2. Inhibitors of bacterial protein synthesis; 3. Synthetic antibacterial agents and miscellaneous antibiotics; 4. Antifungal agents; 5. Antiprotozoal and anthelminthic agents; 6. Antiviral agents; 7. Antiretroviral agents; PART 2: RESISTANCE TO ANTIMICROBIAL AGENTS; 8. The problem of resistance; 9. Mechanisms of acquired resistance; 10. Genetics of resistance; 11. Control of the spread of resistance; PART 3: GENERAL PRINCIPLES OF USAGE OF ANTIMICROBIAL AGENTS; 12. Use of the laboratory; 13. General principles of the treatment of infection; 14. Pharmacokinetics; 15. Prescribing for children and the elderly; 16. Adverse reactions; 17. Chemoprophylaxis; 18. Guidelines, formularies and antimicrobial policies; PART 4: THERAPEUTIC USE OF ANTIMICROBIAL AGENTS; 19. Respiratory tract infections; 20. Urinary infections; 21. Gastrointestinal infections; 22. Bacteraemia and endocarditis; 23. Skin and soft tissue infections; 24. Bone and joint infections; 25. Mycobacterial disease; 26. Infections of the central nervous system; 27. Viral infections; 28. Infection in immunocompromised patients including HIV/AIDS; 29. Sexually transmitted infections; 30. Parasitic diseases; 31. Topical use of antimicrobial agents; 32. Postscript: The development and marketing of antimicrobial drugs