Apoptosis In Oral Dysplastic Lesions & Oral Squamous Cell Carcinoma
(Sprache: Englisch)
Background: Apoptotic index (AI) using light microscopy as an indirect measure to assess the significance of apoptosis as a proliferative marker in dysplastic lesions and malignant epithelial lesions of the oral cavity. Aims: (1) To quantify the apoptotic...
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Background: Apoptotic index (AI) using light microscopy as an indirect measure to assess the significance of apoptosis as a proliferative marker in dysplastic lesions and malignant epithelial lesions of the oral cavity. Aims: (1) To quantify the apoptotic bodies/cells in oral epithelial dysplastic (OED) lesions and oral squamous cell carcinoma (OSCC). (2) To measure AI in OED and OSCC. (3) To compare AI in OED and OSCC. Settings and Design: The proposed laboratory based retrospective study involved the use of hematoxylin and eosin (H and E) stained slides of previously diagnosed OED lesions and OSCC from institutional archives. Materials and Methods: This study constituted 50 cases, each of H and E stained slides of previously diagnosed cases of OED and OSCC. AI was calculated as the number of apoptotic bodies/cells expressed as a percentage of the total number of nonapoptotic tumor/dysplastic cells counted in each case. Statistics Used: Kruskal-Wallis test and Mann-Whitney test were used. Results: There was a statistically significant increase in AI from OED to OSCC (P = 0.000). Conclusions: Further studies need to be undertaken to understand the apoptotic mechanisms
Autoren-Porträt von Shwetha Nambiar K, Veda Hegde
Nambiar K, ShwethaDr Shwetha Nambiar K has completed her Masters in Dental Surgery(MDS) from SDM dental college, Dharwad which is under top 10 best dental colleges in India. Currently working in Department of Oral Pathology and Microbiology in Ramaiah University of Applied Sciences, Bangalore has more than 45 publications to her credit.
Bibliographische Angaben
- Autoren: Shwetha Nambiar K , Veda Hegde
- 2019, 136 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 6139455022
- ISBN-13: 9786139455027
Sprache:
Englisch
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