Arthritis Research

Immunobiology.- Phenotypic Analysis of B-Cells and Plasma Cells.- Detection of Antigen Specific B-Cells in Tissues.- Single Cell Analysis of Synovial Tissue B-Cells.- Tracking Antigen Specific CD4+ T-Cells With Soluble MHC Molecules.- Analysis of Antigen Reactive T-Cells.- Identification and Manipulation of Antigen Specific T-Cells with Artificial Antigen Presenting Cells.- Analysis of Th1/Th2 T-Cell Subsets.- Analysis of the T-Cell Receptor Repertoire of Synovial T-Cells.- The Assessment of T-Cell Apoptosis in Synovial Fluid.- Assays of T-Cell Contact Dependent Monocyte-Macrophage Functions.- Phenotypic and Functional Analysis of Synovial Natural Killer Cells.- Identification and Isolation of Synovial Dendritic Cells.- Animal Models of Arthritis.- The Use of Animal Models for Rheumatoid Arthritis.- Collagen-Induced Arthritis in Mice.- Collagen-Induced Arthristis in Rats.- Collagen Antibody Induced Arthritis.- Arthritis Induced with Minor Cartilage Proteins.- Murine Antigen-Induced Arthritis.- Pristane-Induced Arthritis in the Rat.- The K/BxN Mouse Model of Inflammatory Arthritis.- Analysis of Arthritic Lesions in the Del1 Mouse.- Application of New Technologies to Define Novel Therapeutic Targets.- Gene Expression Profiling in Rheumatology.- Differential Display Reverse Transcription-Polymerase Chain Reaction to Identify Novel Biomolecules in Arthritis Research.- Two-Dimensional Electrophoresis of Proteins Secreted from Articular Cartilage.- Mapping Lymphocyte Plasma Membrane Proteins.- In Vivo Phage Display Selection in the Human/SCID Mouse Chimera Model for Defining Synovial Specific Determinants.- Adenoviral Targeting of Signal Transduction Pathways in Synovial Cell Cultures.

From the reviews:"This volume excels in the presentation of basic, fundamental techniques requisite in the anaylsis of arthritic disease. Especially well done are the immunobiology and animal model sections." -Doody's Book Review, Weighted Numerical Score:96 - 4 Stars"This multiauthored ... compendium of arthritis research methods and protocols provides pertinent practical information for the bench researcher as well as for the interested clinician. ... It is a worthwhile reference to have in the research laboratory ... . I enthusiastically recommend ... and believe this publication would have broad appeal to the rheumatologic community and to those in related specialties. ... I congratulate the authors on developing an excellent compendium of arthritis research ... ." (Robert J. Quinet, JAMA, April, 2008)

From the reviews:

"This volume excels in the presentation of basic, fundamental techniques requisite in the anaylsis of arthritic disease.  Especially well done are the immunobiology and animal model sections." -Doody's Book Review, Weighted Numerical Score:96 - 4 Stars

"This multiauthored ... compendium of arthritis research methods and protocols provides pertinent practical information for the bench researcher as well as for the interested clinician. ... It is a worthwhile reference to have in the research laboratory ... . I enthusiastically recommend ... and believe this publication would have broad appeal to the rheumatologic community and to those in related specialties. ... I congratulate the authors on developing an excellent compendium of arthritis research ... ." (Robert J. Quinet, JAMA, April, 2008)