Atherosclerosis

in atherosclerosis.- Extracellular vesicles in atherosclerosis research.- The use of wire myography to investigate vascular tone and function.- Pig and mouse models of hyperlipidemia and atherosclerosis.- Use of rabbit models to study atherosclerosis.- Genetically engineered hamster models of dyslipidemia and atherosclerosis.- Atherosclerosis induced by adeno-associated virus encoding gain-of-function PCSK9.- Monitoring leukocyte migration during atherosclerosis in vivo.- Evaluation of plaque burden and lipid content in atherosclerotic plaques.- Monitoring cellularity and expression of key markers in atherosclerotic plaques.- Monitoring cellular proliferation and apoptosis in atherosclerosis plaques and intimal thickenings.- Investigation of atherosclerotic plaque vulnerability.- Use of mouse carotid artery ligation model of intimal thickening to probe vascular smooth muscle cell remodelling and function in atherosclerosis.- Assessing efferocytosis in atherosclerotic lesions in situ.- Monitoring atheroprotective macrophage cholesterol efflux in vivo.- Flow cytometry analysis of hematopoietic stem/progenitor cells and mature blood cell subsets in atherosclerosis.- Whole mount preparation of mouse aorta for confocal microscopy studies of the intima.- Isolation of mouse aortic RNA for transcriptomics.- Redox proteomics analysis of atherosclerotic aortas: Application of the "OxICAT" method.- Intravital microscopy in atherosclerosis research.- Localization of long non-coding RNA in formalin-fixed-paraffin embedded vascular tissue using in-situ hybridization.- In vivo gene editing in lipid and atherosclerosis research.- Laser capture microdissection-based mRNA expression microarrays and single-cell RNA sequencing in atherosclerosis research.- Combined single cell RNA and single cell /beta T cell receptor sequencing of the arterial wall in atherosclerosis.- Tissue clearing approaches in atherosclerosis.- Single cell antibody sequencing in atherosclerosis research.- Flow cytometry and mass cytometry for measuring the immune cell infiltrate in atherosclerotic arteries.- Contrast-enhanced ultrasound molecular imaging in atherosclerosis.- Nanoprobes for computed tomography and magnetic resonance imaging in atherosclerosis research.- Positron emission tomography in atherosclerosis research.- Three-dimensional visualization of atherosclerotic vessels by tissue clearing and light sheet fluorescence microscopy.- Intravascular fluorescence molecular imaging of atherosclerosis.