Bacteriocins, Microcins and Lantibiotics

to the Microcin Session.- Escherichia coli genes regulating the production of microcins MCCB17 and MCCC7.- Uptake and mode of action of the peptide antibiotic microcin B17.- The structure and maturation pathway of microcin B17.- Bacteriocins of Gram-positive bacteria: an opinion regarding their nature, nomenclature and numbers.- Molecular properties of Lactobacillus bacteriocins.- Lactococcal bacteriocins: genetics and mode of action.- to the Lantibiotics session.- Lantibiotics : An overview and conformational studies on Gallidermin and Pep5.- Biosynthesis of the lantibiotic Pep5 and mode of action of type A lantibiotics.- Identification of genes involved in lantibiotic synthesis.- Pore forming bacteriocins.- In vivo properties of colicin A: channel activity and translocation.- Site-directed fluorescence spectroscopy as a tool to study the membrane insertion of colicin A.- Structure-function of the colicin E1 ion channel: voltage-driven translocation and gating of a tetra- (or hexa-) helix channel.- Voltage-dependent gating of colicin E1 channels in planar bilayers.- Immunity to colicins.- Immunity protein to pore forming colicins.- Specificity determinants for the interaction of colicin E9 with its immunity protein.- Structural studies on colicin E3 and its immunity protein.- Study of the import mechanisms of colicins through protein engineering and K+ efflux kinetics.- Import and export of colicin M.- TolA: structure, location and role in the uptake of colicins.- Domains of the Escherichia coli BtuB protein involved in outer membrane association and interaction with colicin translocation components.- A structure-function analysis of BtuB, the E.coli vitamin B12 outer membrane transport protein.- General introduction to the secretion of bacteriocins.- Functioning of the pCloDF13 encoded BRP.- Structure/function relationships in the signal sequence of the colicin A lysis protein.- The secretion of colicin V.- to the session on the evolution of bacteriocins.-