Basic and Clinical Pharmacology

Section I. Basic Principles 1 Introduction 2 Drug Receptors & Pharmacodynamics 3 Pharmacokinetics & Pharmacodynamics: Rational Dosing & the Time Course of Drug Action 4 Drug Biotransformation 5 Basic & Clinical Evaluation of New Drugs Section II. Autonomic Drugs 6 Introduction to Autonomic Pharmacology 7 Cholinoceptor-Activating & Cholinesterase-Inhibiting Drugs 8 Cholinoceptor-Blocking Drugs 9 Adrenoceptor-Activating & Other Sympathomimetic Drugs 10 Adrenoceptor Antagonist Drugs Section III. Cardiovascular-Renal Drugs 11 Antihypertensive Agents 12 Vasodilators & the Treatment of Angina Pectoris 13 Drugs Used in Heart Failure 14 Agents Used in Cardiac Arrhythmias 15 Diuretic Agents Section IV. Drugs With Important Actions on Smooth Muscle 16 Histamine, Serotonin, & the Ergot Alkaloids 17 Vasoactive Peptides 18 The Eicosanoids: Prostaglandins, Thromboxanes, Leukotrienes, & Related Compounds 19 Nitric Oxide, Donors, & Inhibitors 20 Drugs Used in Asthma SectionV. Drugs That Act In The Central Nervous System 21 Introduction to the Pharmacology of CNS Drugs 22 Sedative-Hypnotic Drugs 23 The Alcohols 24 Antiseizure Drugs 25 General Anesthetics 26 Local Anesthetics 27 Skeletal Muscle Relaxants 28 Pharmacologic Management of Parkinsonism & Other Movement Disorders 29 Antipsychotic Agents & Lithium 30 Antidepressant Agents 31 Opioid Analgesics & Antagonists 32 Drugs of Abuse Section VI. Drugs Used to Treat Diseases of the Blood, Inflammation & Gout 33 Agents Used in Anemias; Hematopoietic Growth Factors 34 Drugs Used in Disorders of Coagulation 35 Agents Used in Hyperlipidemia 36 Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Section VII. Endocrine Drugs 37 Hypothalamic & Pituitary Hormones 38 Thyroid & Antithyroid Drugs 39 Adrenocorticosteroids & Adrenocortical Antagonists 40 The Gonadal Hormones & Inhibitors 41 Pancreatic Hormones & Antidiabetic Druigs 42 Agents That Affect Bone Mineral Homeostasis SectionVIII. Chemotherapeutic Drugs 43 {b}-Lactam Antibiotics &

Editor: Bertram G. Katzung, MD, PhD, is Professor Emeritus, Department of Cellular & Molecular Pharmacology, University of California, San Francisco. Associate Editors: Susan Masters, PhD, is Professor of Pharmacology & Academy Chair of Phramacology Education, Department of Cellular & Molecular Pharmacology, University of California, San Francisco. Anthony J. Trevor, PhD, is Professor Emeritus, Department of Cellular & Molecular Pharmacology, University of California, San Francisco.