Basic Virology

- Preface to the First Edition

- Preface to the Second Edition

- Preface to the Third Edition

- Acknowledgments

Part I: Virology and Viral Disease
1. Introduction - the Impact of Viruses on Our View of Life 2
2. An Outline of Virus Replication and Viral Pathogenesis
3. Virus Disease in Populations and Individual Animals
4. Patterns of Some Viral Diseases of Humans

Part II: Basic Properties of Viruses and Virus-Cell Interaction
5. Virus Structure and Classification
6. The Beginning and End of the Virus Replication Cycle
7. Host Immune Response to Viral Infection - The Nature of the Vertebrate Immune Response
8. Strategies to Protect Against and Combat Viral Infection

Part III: Working with Virus
9. Visualization and Enumeration of Virus Particles
10. Replicating and Measuring Biological Activity of Viruses
11. Physical and Chemical Manipulation of the Structural Components of Viruses
12. Characterization of Viral Products Expressed in the Infected Cell
13. Viruses Use Cellular Processes to Express Their Genetic Information

Part IV: Replication Patterns of Specific Viruses
14. Replication of Positive-sense RNA Viruses
15. Replication Strategies of RNA Viruses Requiring RNA-directed mRNA Transcription as the First Step in Viral Gene Expression
16. Replication Strategies of Small and Medium-sized DNA Viruses
17. Replication of Some Nuclear-replicating Eukaryotic DNA Viruses with Large Genomes
18. Replication of Cytoplasmic DNA Viruses and "Large" Bacteriophages
19. Retroviruses: Converting RNA to DNA
20. Human Immunodeficiency Virus Type 1 (HIV-1) and Related Lentiviruses
21. Hepadnaviruses: Variations on the Retrovirus Theme

PART V: Viruses: New Approaches and New Problems
22. The Molecular Genetics of Viruses
23. Molecular Pathogenesis
24. Viral Bioinformatics and Beyond
25. Viruses and the Future - Promises and Problems

- Appendix: Resource Center

- Books of Historical and Basic Value

- Books on Virology

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Edward K. Wagner (May 4, 1940 - January 21, 2006) was Professor of Molecular Biology and Biochemistry at the University of California Irvine. Martinez J. Hewlett is Professor Emeritus in the Department of Molecular and Cellular Biology at the University of Arizona. New to this edition, David C. Bloom is Associate Professor in the Department of Molecular Genetics and Microbiology at University of Florida and David Camerini is Assistant Professor in the Department of Molecular Biology and Biochemistry at the University of California Irvine.

"This latest revision to the very successful Basic Virology is more than just a simple update... The new chapters are very timely and address current virology research topics including the important issues of molecular pathogenesis and bioinformatics. The text is well written and very understandable with excellent use of photos, diagrams, and tables to highlight and aid in the understanding of difficult issues. Instructors will find the text up to date and the figures readily adaptable to Powerpoint lectures. Students will be pleased to find the text engaging while presenting virology in a clear, concise, and enjoyable manner."
Professor Michael R. Roner, University of Texas, Arlington