Chemical Toxicity for Some Non-Steroidal Anti-Inflammatory Drugs
Evaluations of Chemical Constituents and In Silico Prediction
(Sprache: Englisch)
The non-steroidal anti-inflammatory drugs (NSAIDs) are among the most successful medicines in the world, being used by large numbers of patients, due to their anti-inflammatory, analgesic, and antipyretic effects. But these NSAIDs are associated with...
Leider schon ausverkauft
versandkostenfrei
Buch
39.90 €
19 DeutschlandCard Punkte
sammeln
- Lastschrift, Kreditkarte, Paypal, Rechnung
- Kostenlose Rücksendung
Produktdetails
Produktinformationen zu „Chemical Toxicity for Some Non-Steroidal Anti-Inflammatory Drugs “
Klappentext zu „Chemical Toxicity for Some Non-Steroidal Anti-Inflammatory Drugs “
The non-steroidal anti-inflammatory drugs (NSAIDs) are among the most successful medicines in the world, being used by large numbers of patients, due to their anti-inflammatory, analgesic, and antipyretic effects. But these NSAIDs are associated with several side effects such as vomiting, diarrhea, headache, kidney failure, liver failure, ulcers, etc. Molecular structure proprieties were investigated using density functional theory (DFT) via B3LYP/6-31G (d,p), using the Gaussian 09 program. Here, we present ProTox-II that incorporates molecular similarity, pharmacophores, fragment propensities, and machine-learning models for the prediction of various toxicity endpoints; such as acute toxicity, hepatotoxicity, cytotoxicity, carcinogenicity, mutagenicity, immunotoxicity, adverse outcomes pathways (Tox21), and toxicity targets. In view of the above-noticed facts and continuation of our interest evaluations of chemical constituents and in-silico prediction of chemical toxicity for some non-steroidal anti-inflammatory drugs.
Autoren-Porträt von Palanisamy Pandaram
Pandaram, PalanisamyPandaram Palanisamy has been working as an Assistant Professor of Chemistry at the Pioneer Kumaraswamy College, Nagercoil-629003. He is working in the field of Synthetic Organic Chemistry and Crystal Growth.
Bibliographische Angaben
- Autor: Palanisamy Pandaram
- 2020, 76 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 6202921536
- ISBN-13: 9786202921534
Sprache:
Englisch
Kommentar zu "Chemical Toxicity for Some Non-Steroidal Anti-Inflammatory Drugs"
0 Gebrauchte Artikel zu „Chemical Toxicity for Some Non-Steroidal Anti-Inflammatory Drugs“
| Zustand | Preis | Porto | Zahlung | Verkäufer | Rating |
|---|
Schreiben Sie einen Kommentar zu "Chemical Toxicity for Some Non-Steroidal Anti-Inflammatory Drugs".
Kommentar verfassen