Computational analysis of STMADS11 MADS-box regulatory elements
analysis underlying expression divergence
(Sprache: Englisch)
Functions of orthologs may diverge during evolution either due to alteration of cis-regulatory elements or changes in the coding regions. The STMADS11 superclade MADS-box genes play diverse roles in plants; implicated in vegetative development, phase...
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Functions of orthologs may diverge during evolution either due to alteration of cis-regulatory elements or changes in the coding regions. The STMADS11 superclade MADS-box genes play diverse roles in plants; implicated in vegetative development, phase transition, floral meristem identity, male fertility and inflated calyx. Phylogenetic reconstruction revealed three distinct clades comprising MPF1-like, MPF2-like and SVP-like. Expression analysis indicated inter and intra-clade expression divergence with regard to their expression in vegetative and floral tissues. The MADS-domain HCTs were predominantly located in the promoter regions. These MADS-domain HCTs are located in the vicinity of the TSS seemed to be involved in regulating expression in sepal, particularly in case of MPF2-like clade. Phylogenetic foot printing of -2kb STMADS11 promoter sequences highlighted two conserve regions; immediately upstream of TSS site and proximal to TSS. These regions have evolved under negativeselection. A comprehensive understanding of the role of STMADS11 cis-regulatory elements in expression divergence is though enigmatic, this study highlights the significance of cis-regulatory elements.
Bibliographische Angaben
- Autoren: Tajammul Hussain , Muhammad Ramzan Khan
- 2013, 124 Seiten, Maße: 22 cm, Kartoniert (TB), Englisch
- Verlag: LAP Lambert Academic Publishing
- ISBN-10: 3847326716
- ISBN-13: 9783847326717
Sprache:
Englisch
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