Designs for Clinical Trials
Perspectives on Current Issues
(Sprache: Englisch)
This book examines current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, the design of studies in which missing data is anticipated.
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This book examines current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, the design of studies in which missing data is anticipated.
Klappentext zu „Designs for Clinical Trials “
This book will examine current issues and controversies in the design of clinical trials, including topics in adaptive and sequential designs, the design of correlative genomic studies, the design of studies in which missing data is anticipated. Each chapter will be written by an expert conducting research in the topic of that chapter. As a collection, the chapters would be intended to serve as a guidance for statisticians designing trials.
Inhaltsverzeichnis zu „Designs for Clinical Trials “
New designs for phase I dose finding studies.- Phase II/III designs for trials.- Design issues for clinical studies with genomic measurements.- Designing studies with longitudinal measurements subject to dropout.- Issues in sample size re-estimation.- Adaptive designs.- The design of non-inferiority trials.- Issues in the design of HIV prevention trials.- Randomization algorithms.- Sequential designs for phase III studies.- Case studies of difficult designs.- Ethical issues in the design of trials.- Index.
Bibliographische Angaben
- 2013, 2012, XIV, 206 Seiten, Maße: 15,6 x 23,3 cm, Kartoniert (TB), Englisch
- Herausgegeben: David Harrington
- Verlag: Springer, Berlin
- ISBN-10: 1461429536
- ISBN-13: 9781461429531
Sprache:
Englisch
Pressezitat
From the reviews:"'Designs for Clinical Trials: Perspectives on Current Issues' fills the gap between professional journals and school textbooks by addressing a few important, rapidly evolving statistical topics. The book is intended for statistical practitioners like clinical trialists who actively use statistics but do not follow the literature on recent biostatistical thinking." (Norman M. Goldfarb, Journal of Clinical Research Best Practices, Vol. 9 (2), February, 2013)
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